Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

[HTML][HTML] Nanomaterials for cancer therapy: current progress and perspectives

Z Cheng, M Li, R Dey, Y Chen - Journal of hematology & oncology, 2021 - Springer
Cancer is a disease with complex pathological process. Current chemotherapy faces
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …

[HTML][HTML] Methods of liposomes preparation: Formation and control factors of versatile nanocarriers for biomedical and nanomedicine application

D Lombardo, MA Kiselev - Pharmaceutics, 2022 - mdpi.com
Liposomes are nano-sized spherical vesicles composed of an aqueous core surrounded by
one (or more) phospholipid bilayer shells. Owing to their high biocompatibility, chemical …

[HTML][HTML] Immune-mediated approaches against COVID-19

HF Florindo, R Kleiner, D Vaskovich-Koubi… - Nature …, 2020 - nature.com
Abstract The coronavirus disease-19 (COVID-19) is caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The long incubation period of this new virus, which …

[HTML][HTML] Protein-based nanoparticles as drug delivery systems

S Hong, DW Choi, HN Kim, CG Park, W Lee, HH Park - Pharmaceutics, 2020 - mdpi.com
Pharmaceutics | Free Full-Text | Protein-Based Nanoparticles as Drug Delivery Systems Next
Article in Journal Exploiting Lipid and Polymer Nanocarriers to Improve the Anticancer …

[HTML][HTML] Nano based drug delivery systems: recent developments and future prospects

JK Patra, G Das, LF Fraceto, EVR Campos… - Journal of …, 2018 - Springer
Nanomedicine and nano delivery systems are a relatively new but rapidly developing
science where materials in the nanoscale range are employed to serve as means of …

[HTML][HTML] The regulation of nanomaterials and nanomedicines for clinical application: Current and future perspectives

R Foulkes, E Man, J Thind, S Yeung, A Joy… - Biomaterials …, 2020 - pubs.rsc.org
The use of nanomaterials in biomedicine has increased over the past 10 years, with many
different nanoparticle systems being utilised within the clinical setting. With limited emerging …

PEGylated lipid nanoparticle formulations: immunological safety and efficiency perspective

R Tenchov, JM Sasso, QA Zhou - Bioconjugate chemistry, 2023 - ACS Publications
Lipid nanoparticles (LNPs) have been recognized as efficient vehicles to transport a large
variety of therapeutics. Currently in the spotlight as important constituents of the COVID-19 …

Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

[HTML][HTML] Current trends and challenges in the clinical translation of nanoparticulate nanomedicines: pathways for translational development and commercialization

S Hua, MBC De Matos, JM Metselaar… - Frontiers in …, 2018 - frontiersin.org
The use of nanotechnology in medicine has the potential to have a major impact on human
health for the prevention, diagnosis, and treatment of diseases. One particular aspect of the …