Inflammatory bowel disease (IBD) is a general term for chronic or remitting/relapsing
inflammatory diseases of the intestinal tract and generally refers to ulcerative colitis (UC) …

Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

Various therapeutic advances have led to a paradigm shift in the clinical management of
patients with IBD. The introduction of immunosuppressive (such as azathioprine) and …

Background Inflammatory bowel diseases [IBD]―ulcerative colitis and Crohn's disease―are
commonly treated with biologic drugs. However, only approximately two-thirds of patients …

Background There are limited data to inform positioning of agents for treating moderate‐
severe Crohn's disease (CD). Aim We assessed comparative efficacy and safety of first‐line …

Background & Aims Vedolizumab is a gut-selective monoclonal antibody for the treatment of
moderately to severely active Crohn's disease (CD). We performed a prospective study of …

Background Fecal microbiota transplantation (FMT) is highly effective for treating recurrent
Clostridium difficile infection (CDI) in observational studies (> 90%), but cure rates in clinical …

Various lifestyle factors including physical activity and obesity, stress, sleep, and smoking
may modify the risk of developing inflammatory bowel diseases (IBDs). In patients with …

OBJECTIVES: We aimed to quantify the safety and effectiveness of vedolizumab (VDZ)
when used for UC, and to identify predictors of response to treatment. METHODS …

Background Selective patient recruitment can produce discrepancies between clinical trial
results and real-world effectiveness. Methods A systematic literature review and meta …