Glycosylation is the most abundant and complex protein modification, and can have a
profound structural and functional effect on the conjugate. The oligosaccharide fraction is …

Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …

N-linked glycosylation is a biologically important protein modification, but only a small
fraction of modification sites have been mapped. We developed a" filter aided sample …

Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …

Post-translational modifications generate tremendous diversity, complexity and
heterogeneity of gene products, and their determination is one of the main challenges in …

The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

Replicate mass spectrometry (MS) measurements and the use of multiple analytical
methods can greatly expand the comprehensiveness of shotgun proteomic profiling of …

Glycosylation is one of the most common post-translational modifications (PTMs) of proteins.
At least 50% of human proteins are glycosylated with some estimates being as high as 70 …

Next to the identification of proteins and the determination of their expression levels, the
analysis of post-translational modifications (PTM) is becoming an increasingly important …

The enormous complexity, wide dynamic range of relative protein abundances of interest
(over 10 orders of magnitude), and tremendous heterogeneity (due to post-translational …