Fluorescence nanoscopy in cell biology
Fluorescence nanoscopy uniquely combines minimally invasive optical access to the
internal nanoscale structure and dynamics of cells and tissues with molecular detection …
internal nanoscale structure and dynamics of cells and tissues with molecular detection …
A review of super-resolution single-molecule localization microscopy cluster analysis and quantification methods
Single-molecule localization microscopy (SMLM) is a relatively new imaging modality,
winning the 2014 Nobel Prize in Chemistry, and considered as one of the key super …
winning the 2014 Nobel Prize in Chemistry, and considered as one of the key super …
Single-molecule localization microscopy in eukaryotes
M Sauer, M Heilemann - Chemical reviews, 2017 - ACS Publications
Super-resolution fluorescence imaging by photoactivation or photoswitching of single
fluorophores and position determination (single-molecule localization microscopy, SMLM) …
fluorophores and position determination (single-molecule localization microscopy, SMLM) …
Canonical T cell receptor docking on peptide–MHC is essential for T cell signaling
INTRODUCTION T cell receptor (TCR) recognition of peptide–major histocompatibility
complexes (pMHCs) is one of the most diverse receptor–ligand interactions in biology …
complexes (pMHCs) is one of the most diverse receptor–ligand interactions in biology …
[HTML][HTML] Super-resolution imaging of higher-order chromatin structures at different epigenomic states in single mammalian cells
Histone modifications influence higher-order chromatin structures at individual epigenomic
states and chromatin environments to regulate gene expression. However, genome-wide …
states and chromatin environments to regulate gene expression. However, genome-wide …
The human integrator complex facilitates transcriptional elongation by endonucleolytic cleavage of nascent transcripts
Transcription by RNA polymerase II (RNAPII) is pervasive in the human genome. However,
the mechanisms controlling transcription at promoters and enhancers remain enigmatic …
the mechanisms controlling transcription at promoters and enhancers remain enigmatic …
Concentric organization of A-and B-type lamins predicts their distinct roles in the spatial organization and stability of the nuclear lamina
The nuclear lamina is an intermediate filament meshwork adjacent to the inner nuclear
membrane (INM) that plays a critical role in maintaining nuclear shape and regulating gene …
membrane (INM) that plays a critical role in maintaining nuclear shape and regulating gene …
About samples, giving examples: optimized single molecule localization microscopy
A Jimenez, K Friedl, C Leterrier - Methods, 2020 - Elsevier
Super-resolution microscopy has profoundly transformed how we study the architecture of
cells, revealing unknown structures and refining our view of cellular assemblies. Among the …
cells, revealing unknown structures and refining our view of cellular assemblies. Among the …
Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors
M Wegrecki, TA Ocampo, SD Gunasinghe… - Nature …, 2022 - nature.com
CD1a is a monomorphic antigen-presenting molecule on dendritic cells that presents lipids
to αβ T cells. Whether CD1a represents a ligand for other immune receptors remains …
to αβ T cells. Whether CD1a represents a ligand for other immune receptors remains …
Digital pathology analysis quantifies spatial heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 immune markers in triple-negative breast cancer
Overwhelming evidence has shown the significant role of the tumor microenvironment (TME)
in governing the triple-negative breast cancer (TNBC) progression. Digital pathology can …
in governing the triple-negative breast cancer (TNBC) progression. Digital pathology can …