Animal models for the study of leishmaniasis immunology

EN Loría-Cervera, FJ Andrade-Narváez - Revista do Instituto de …, 2014 - SciELO Brasil
Leishmaniasis remains a major public health problem worldwide and is classified as
Category I by the TDR/WHO, mainly due to the absence of control. Many experimental …

Experimental models for leishmaniasis and for testing anti-leishmanial vaccines

M Hommel, CL Jaffe, B Travi, G Milon - Annals of Tropical …, 1995 - Taylor & Francis
In public health terms, leishmaniases are diseases of humans and dogs, whereas, in
epidemiological terms, Leishmania spp. are considered to represent infections of a wide …

The Ibizian hound presents a predominantly cellular immune response against natural Leishmania infection

L Solano-Gallego, J Llull, G Ramos, C Riera… - Veterinary …, 2000 - Elsevier
Veterinarians working in the Balearic Islands (Mallorca), an endemic region of canine
leishmaniosis, have reported very few cases of leishmaniosis in Ibizian hounds while …

Isotype patterns of immunoglobulins: hallmarks for clinical status and tissue parasite density in Brazilian dogs naturally infected by Leishmania (Leishmania) chagasi

AB Reis, A Teixeira-Carvalho, AM Vale… - Veterinary immunology …, 2006 - Elsevier
The role of anti-leishmanial immune response underlying the susceptibility/resistance during
canine visceral leishmaniasis (CVL) has been recognized throughout ex vivo and in vitro …

Analysis of the humoral immune response against total and recombinant antigens of Leishmania infantum: correlation with disease progression in canine …

CG Nieto, M Garcıa-Alonso, JM Requena… - Veterinary Immunology …, 1999 - Elsevier
Leishmaniasis by Leishmania infantum in the Mediterranean Basin constitutes an important
problem in both human and veterinary medicine. Based in both the importance of canids as …

[HTML][HTML] Naturally acquired visceral leishmaniasis in non-human primates in Brazil

MCC Malta, HP Tinoco, MN Xavier, ALS Vieira… - Veterinary …, 2010 - Elsevier
Visceral leishmaniasis (VL) is a chronic and often fatal protozoal disease that is endemic in
Belo Horizonte (State of Minas Gerais, Brazil). Leishmania sp. is an intracellular obligatory …

[图书][B] Handbook of Laboratory Animal Science: Animal Models, Volume II

J Hau, SJ Schapiro, GL Van Hoosier Jr - 2002 - taylorfrancis.com
The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

Vervet Monkeys Vaccinated with Killed Leishmania major Parasites and Interleukin-12 Develop a Type 1 Immune Response but Are Not Protected against Challenge …

MM Gicheru, JO Olobo, CO Anjili, AS Orago… - Infection and …, 2001 - Am Soc Microbiol
Leishmania major is a protozoan parasite that causes chronic cutaneous lesions that often
leave disfiguring scars. Infections in mice have demonstrated that leishmanial vaccines that …

Progress in vaccine research and possible effector mechanisms in visceral leishmaniasis

R Ravindran, N Ali - Current molecular medicine, 2004 - ingentaconnect.com
Visceral leishmaniasis represents a serious public health concern in endemic regions and is
rapidly emerging as an opportunistic infection in HIV patients. The disease is difficult to …

Leishmania infantum-induced primary and challenge infections in rhesus monkeys (Macaca mulatta): a primate model for visceral leishmaniasis

R Porrozzi, MS Pereira, A Teva… - Transactions of the …, 2006 - academic.oup.com
Visceral leishmaniasis (VL) was experimentally induced in rhesus macaques (Macaca
mulatta) by intravenously inoculating 2× 107 amastigotes/kg of body weight of Leishmania …