Objectives To inform the 2019 update of the European League against Rheumatism
(EULAR) recommendations for the management of rheumatoid arthritis (RA). Methods A …

Objectives To perform a systematic literature review (SLR) concerning the safety of synthetic
(s) and biological (b) disease-modifying anti rheumatic dugs (DMARDs) to inform the 2019 …

Abstract Purpose of Review Adalimumab is one of the top-selling drugs worldwide. Its
imminent patent expiration has seen the emergence of numerous biosimilar agents. In this …

Objective To compare the efficacy, serum drug concentrations, immunogenicity, and safety
of FKB327 with the adalimumab reference product (RP) in combination with methotrexate in …

Importance Biosimilar drugs are potentially lower-cost versions of biologics that may
improve access to therapy. However, there is a lack of adequate systematic reviews …

Rheumatoid arthritis (RA) affects around 1.2% of the adult population. RA is one of the main
reasons for work disability and premature retirement, thus substantially increasing social …

Objectives To evaluate the efficacy and safety of biosimilars compared with reference
biological disease modifying antirheumatic drugs (bDMARDs) in patients with rheumatoid …

Biologic drugs have revolutionized the treatment of psoriasis and other rheumatological
diseases. In recent years, many biosimilar agents that are highly similar in structure and …

Few studies compared adalimumab to other targeted therapies in head-to-head randomized
clinical trials (RCTs) for rheumatoid arthritis (RA), but multiple comparisons are not …

Purpose This study aimed to evaluate biosimilar adalimumab's efficacy and safety in
patients with Behçet's uveitis in Iran. Methods We performed a study on patients who mostly …