The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …

Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …

At present, some progress has been made in the field of cancer theranostics based on
nanocatalysts (NCs), but achieving precise theranostics in response to the specific tumor …

Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

The tumor microenvironment (TME) featured by immunosuppression and hypoxia is pivotal
to cancer deterioration and metastasis. Thus, regulating the TME to improve cancer cell …

Combining immune checkpoint blockade (ICB) therapy with photodynamic therapy (PDT)
holds great potential in treating immunologically “cold” tumors, but photo-generated reactive …

Simultaneous targeting of both the tumor microenvironment and cancer cells by a single
nanomedicine has not been reported to date. Here, we report the dual properties of zero …

Immunomodulation of macrophages against cancer has emerged as an encouraging
therapeutic strategy. However, there exist two major challenges in effectively activating …

Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …

External stimuli-responsive nanomedicine with desirable repetitive on-demand drug release
character is postulated to greatly accommodate patients' flexible medication regime. To this …