Abstract Tamoxifen (ICI 46 474), trans-1-(4-β-dimethylaminoethoxyphenyl)-1, 2-diphenylbut-
1-ene, is the most commonly used drug for the treatment of estrogen receptor positive breast …

Estrogen receptors (ERs) are a group of compounds named for their importance in both
menstrual and estrous reproductive cycles. They are involved in the regulation of various …

In the search for new and effective treatments of breast and prostate cancer, a series of
hybrid compounds based on tamoxifen, estrogens, and artemisinin were successfully …

Synthesis and antimalarial activity of 94 novel bipyrrole tambjamines (TAs) and a library of B-
ring functionalized tripyrrole prodiginines (PGs) against a panel of Plasmodium falciparum …

Prodigiosin is the parent compound of the tripyrrolic natural products known as the
prodigiosenes. Some of these natural products and their synthetic analogs show anti …

Research of steroidal compounds as anticancer agents started almost 50 years ago. During
the past decades, several innovative new steroids, like cyproterone, finasteride, estramustin …

Steroid and its derivatives have been proved to have important and diverse biological
functions, which present the wide spectrum of biological activities such as antitumor …

Several analogues of the natural compound prodigiosin with modified A-and C-rings were
synthesised as were some of their tin, cobalt, boron and zinc complexes. The antimalarial …

Facile and highly efficient synthetic routes for the synthesis of (S)-and (R)-23-
hydroxyundecylprodiginines ((23 S)-2, and (23 R)-2), 23-ketoundecylprodiginine (3), and …

Prodiginines, as a family of bacterial alkaloids, possess a number of interesting biological
activities. New, concise synthetic routes for the facile preparation of both synthetic and …