A Cross Talk between the Endocannabinoid System and Different Systems Involved in the Pathogenesis of Hypertensive Retinopathy

FK Alswailmi - Pharmaceuticals, 2023 - mdpi.com
The prognosis of hypertension leads to organ damage by causing nephropathy, stroke,
retinopathy, and cardiomegaly. Retinopathy and blood pressure have been extensively …

Collecting duct-specific knockout of sphingosine-1-phosphate receptor 1 aggravates DOCA-salt hypertension in mice

G Hu, Q Zhu, W Wang, D Xie, C Chen, PL Li… - Journal of …, 2021 - journals.lww.com
Objective: We have previously reported that renal medullary sphingosine-1-phosphate
(S1P) regulates sodium excretion via the S1P type-1 receptor (S1PR1). As S1PR1 is …

[PDF][PDF] Endocannabinoid system: An untold story in hypertensive nephropathy.

A Ahmad - Electronic Journal of General Medicine, 2023 - ejgm.co.uk
Prognosis of hypertension leads to organ damage by causing nephropathy, stroke,
retinopathy and cardiomegaly. Kidney, retinopathy and blood pressure (BP) have been …

Connexin43 is differentially distributed within renal vasculature and mediates profibrotic differentiation in medullary fibroblasts

Y Xu, J Hu, DE Yilmaz… - American Journal of …, 2021 - journals.physiology.org
Connexins (Cxs) form gap junctions for intercellular exchange of inorganic ions and
messenger molecules. In the kidney, Cxs play essential roles within its compartments, but …

Renal medullary overexpression of sphingosine-1-phosphate receptor 1 transgene attenuates deoxycorticosterone acetate (DOCA)-salt hypertension

G Hu, D Xie, C Chen, W Wang, PL Li… - American Journal of …, 2023 - academic.oup.com
BACKGROUND Our previous studies showed that renal medullary sphingosine-1-
phosphate receptor 1 (S1PR1) mediated sodium excretion, high salt intake increased …

Renomedullary interstitial cell endothelin A receptors regulate BP and renal function

C Hu, J Lakshmipathi, D Stuart… - Journal of the …, 2020 - journals.lww.com
Background The physiologic role of renomedullary interstitial cells, which are uniquely and
abundantly found in the renal inner medulla, is largely unknown. Endothelin A receptors …