NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
P Paoletti, C Bellone, Q Zhou - Nature Reviews Neuroscience, 2013 - nature.com
NMDA receptors (NMDARs) are glutamate-gated ion channels and are crucial for neuronal
communication. NMDARs form tetrameric complexes that consist of several homologous …
communication. NMDARs form tetrameric complexes that consist of several homologous …
NMDA receptor functions in health and disease: Old actor, new dimensions
N-Methyl-D-aspartate ionotropic glutamate receptors (NMDARs) play key roles in
synaptogenesis, synaptic maturation, long-term plasticity, neuronal network activity, and …
synaptogenesis, synaptic maturation, long-term plasticity, neuronal network activity, and …
Multiple sclerosis and cognition: synaptic failure and network dysfunction
M Di Filippo, E Portaccio, A Mancini… - Nature Reviews …, 2018 - nature.com
Cognitive impairment is increasingly recognized to be a core feature of multiple sclerosis
(MS), with important implications for the everyday life of individuals with MS and for disease …
(MS), with important implications for the everyday life of individuals with MS and for disease …
Hippocampal insulin resistance impairs spatial learning and synaptic plasticity
CA Grillo, GG Piroli, RC Lawrence, SA Wrighten… - Diabetes, 2015 - Am Diabetes Assoc
Insulin receptors (IRs) are expressed in discrete neuronal populations in the central nervous
system, including the hippocampus. To elucidate the functional role of hippocampal IRs …
system, including the hippocampus. To elucidate the functional role of hippocampal IRs …
Na+/K+-pump and neurotransmitter membrane receptors
AS Pivovarov, F Calahorro, RJ Walker - Invertebrate Neuroscience, 2019 - Springer
Abstract Na+/K+-pump is an electrogenic transmembrane ATPase located in the outer
plasma membrane of cells. The Na+/K+-ATPase pumps 3 sodium ions out of cells while …
plasma membrane of cells. The Na+/K+-ATPase pumps 3 sodium ions out of cells while …
GluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity
OA Shipton, O Paulsen - Philosophical Transactions of …, 2014 - royalsocietypublishing.org
N-Methyl-d-aspartate receptor (NMDAR)-dependent synaptic plasticity is a strong candidate
to mediate learning and memory processes that require the hippocampus. This plasticity is …
to mediate learning and memory processes that require the hippocampus. This plasticity is …
Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning
JL Brigman, T Wright, G Talani… - Journal of …, 2010 - Soc Neuroscience
NMDA receptors (NMDARs) are key mediators of certain forms of synaptic plasticity and
learning. NMDAR complexes are heteromers composed of an obligatory GluN1 subunit and …
learning. NMDAR complexes are heteromers composed of an obligatory GluN1 subunit and …
Effects of central and peripheral inflammation on hippocampal synaptic plasticity
The central nervous system (CNS) and the immune system are known to be engaged in an
intense bidirectional crosstalk. In particular, the immune system has the potential to …
intense bidirectional crosstalk. In particular, the immune system has the potential to …
Astrocytes and human cognition: modeling information integration and modulation of neuronal activity
A Pereira Jr, FA Furlan - Progress in neurobiology, 2010 - Elsevier
Recent research focusing on the participation of astrocytes in glutamatergic tripartite
synapses has revealed mechanisms that support cognitive functions common to human and …
synapses has revealed mechanisms that support cognitive functions common to human and …
Differential nanoscale topography and functional role of GluN2-NMDA receptor subtypes at glutamatergic synapses
B Kellermayer, JS Ferreira, J Dupuis, F Levet… - Neuron, 2018 - cell.com
NMDA receptors (NMDARs) play key roles in the use-dependent adaptation of glutamatergic
synapses underpinning memory formation. In the forebrain, these plastic processes involve …
synapses underpinning memory formation. In the forebrain, these plastic processes involve …