Role and mechanism of CD90+ fibroblasts in inflammatory diseases and malignant tumors

F Zeng, M Gao, S Liao, Z Zhou, G Luo, Y Zhou - Molecular medicine, 2023 - Springer
Fibroblasts are highly heterogeneous mesenchymal stromal cells, and different fibroblast
subpopulations play different roles. A subpopulation of fibroblasts expressing CD90, a 25 …

Thy-1 (CD90), integrins and syndecan 4 are key regulators of skin wound healing

LA Pérez, L Leyton, A Valdivia - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Acute skin wound healing is a multistage process consisting of a plethora of tightly regulated
signaling events in specialized cells. The Thy-1 (CD90) glycoprotein interacts with integrins …

[HTML][HTML] Dysregulation of interaction between LOXhigh fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection

Y Chen, T Zhang, F Yao, X Gao, D Li, S Fu, L Mao… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: While cell-cell interaction plays a critical role in physiology and disease, a
comprehensive understanding of its dynamics in vascular homeostasis and diseases is yet …

[HTML][HTML] Chrysin and Capsaicin induces premature senescence and apoptosis via mitochondrial dysfunction and p53 elevation in Cervical cancer cells

JS Pawar, S Mustafa, I Ghosh - Saudi journal of biological sciences, 2022 - Elsevier
Current studies are focusing on the anti-cancerous properties of natural bioactive
compounds, primarily those included in the human diet. These compounds have the …

CD34+THY1+ synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro

S Noda, T Hosoya, Y Komiya, Y Tagawa… - Arthritis research & …, 2022 - Springer
Abstract Objective Synovial fibroblasts (SFs) in rheumatoid arthritis (RA) and osteoarthritis
(OA) play biphasic roles in joint destruction and regeneration of bone/cartilage as …

Integrated single-cell RNA sequencing analysis reveals a mesenchymal stem cell-associated signature for estimating prognosis and drug sensitivity in gastric cancer

K Shen, B Chen, W Gao - Journal of Cancer Research and Clinical …, 2023 - Springer
Abstract Background Mesenchymal stem cells (MSCs) play an important role in regulating
all stages of the immune response, angiogenesis, and transformation of matrix components …

Selenoprotein I deficiency in T cells promotes differentiation into tolerant phenotypes while decreasing Th17 pathology

C Ma, FKW Hoffmann, LG Nunes… - Journal of leukocyte …, 2022 - academic.oup.com
Selenoprotein I (SELENOI) is an ethanolamine phospholipid transferase contributing to
cellular metabolism and the synthesis of glycosylphosphatidylinositol (GPI) anchors …

Antifibrotic soluble thy-1 correlates with renal dysfunction in chronic kidney disease

A Saalbach, U Anderegg, R Wendt, J Beige… - International Journal of …, 2023 - mdpi.com
Kidney fibrosis is a major culprit in the development and progression of chronic kidney
disease (CKD), ultimately leading to the irreversible loss of organ function. Thymocyte …

Nogo-A regulates the fate of human dental pulp stem cells toward osteogenic, adipogenic, and neurogenic differentiation

CF Lai, J Shen, A Balic, P Pagella, ME Schwab… - Cells, 2022 - mdpi.com
Human teeth are highly innervated organs that contain a variety of mesenchymal stem cell
populations that could be used for cell-based regenerative therapies. Specific molecules are …

[HTML][HTML] Markers of Dermal Fibroblast Subpopulations for Viable Cell Isolation via Cell Sorting: A Comprehensive Review

K Łuszczyński, M Soszyńska, M Komorowski… - Cells, 2024 - mdpi.com
Fibroblasts are among the most abundant cell types in the human body, playing crucial roles
in numerous physiological processes, including the structural maintenance of the dermis …