Osteocalcin (Ocn), which is specifically produced by osteoblasts, and is the most abundant
non-collagenous protein in bone, was demonstrated to inhibit bone formation and function …

Osteoblasts are specialized mesenchymal cells that synthesize bone matrix and coordinate
the mineralization of the skeleton. These cells work in harmony with osteoclasts, which …

The strength of bone depends on bone quantity and quality. Osteocalcin (Ocn) is the most
abundant noncollagenous protein in bone and is produced by osteoblasts. It has been …

Protein extracts derived from bone can initiate the process that begins with cartilage
formation and ends in de novo bone formation. The critical components of this extract …

The implantation of bone morphogenetic protein (BMP) into muscular tissues induces
ectopic bone formation at the site of implantation. To investigate the mechanism underlying …

Blood coagulation is a host defense system that assists in maintaining the integrity of the
closed, high-pressure mammalian circulatory system after blood vessel injury. After initiation …

A series of subclonal cell lines with high or low differentiation/mineralization potential after
growth in the presence of ascorbic acid (AA) were derived from murine MC3T3‐E1 cells …

In addition to its structural role, the skeleton serves as an endocrine organ that controls
mineral metabolism and energy homeostasis. Three major cell types in bone-osteoblasts …

The combined application of molecular, biochemical, histochemical, and ultrastructural
approaches has defined a temporal sequence of gene expression associated with …

Containing fully authenticated data on virtually all known natural products, the" Dictionary of
Natural Products", main work, published in 1993 was the end result of over 12 years …