Besides its well‐known regulatory role on circadian rhythm, the pineal gland hormone
melatonin has other biological functions and a distinct metabolism in various cell types and …

The antioxidant properties of melatonin can be successfully used to reduce the effects of
oxidative stress caused by homocysteine. The beneficial actions of melatonin are mainly …

Abstract Aim Hyperhomocysteinemia and homocysteine (Hcy) mediated dopaminergic
neurotoxicity is a matter of concern in the pathophysiology of Parkinson's disease (PD). Our …

Nitrous oxide is a widely used analgesic agent, used also in combination with anaesthetics
during surgery. Recent research has raised concerns about possible neurotoxicity of nitrous …

Age related neurodegenerative disorders are becoming a serious public health problem.
Alzheimer's disease (AD) is a progressive disease pathologically recognizable by …

Bipolar disorder (BD) is a long-recognized severe and common psychiatric disorder, with a
complex and often diverse range of presentations. BD is a heterogenous disorder that has …

Aim: To examine whether danshensu could protect vascular endothelia in a rat model of
hyperhomocysteinemia. Methods: The model was established by feeding rats with a …

Context: Melatonin, a pineal hormone and a potent antioxidant, has important roles in
metabolic regulation. Objective: This study investigated serum asymmetric dimethylarginine …

Macrophage-derived foam cells are well known for their key role in development of
atherosclerosis (AS). The present study aimed to examine whether dioscin exerts anti …

The purpose of this study was to develop a chronic chemically induced model of mild
hyperhomocysteinemia in adult rats. We produced levels of Hcy in the blood (30μM) …