Metabolomics and exposomics are important in the studies of human health and diseases.
Chemical isotope labeling (CIL) combined with mass spectrometry (MS) can not only …

Derivatization, or chemical structure modification, is often used in bioanalysis performed by
liquid chromatography technique in order to enhance detectability or to improve the …

Although chemoselective labeling strategies show great potential in in‐depth description of
metabolomics, the associated time and expense limit applications in high‐throughput and …

RNA modifications have been revealed to be essential in many biological activities, and
their disorders are associated with various human diseases, including cancers. 2′-O …

Fatty aldehydes (FALs) are involved in various biological processes, and their abnormal
metabolism is related to the occurrence and development of neurological diseases …

Colorectal cancer (CRC) is a common malignant tumor in the gastrointestinal tract. Changes
in amino acid metabolites have been implicated in tumorigenesis and disease progression …

Abstract Small biomolecules (m/z< 500) are the material basis of organisms and participate
in life activities, but their comprehensive and accurate detection in complex samples …

RNA methylation plays a vital role in the pathogenesis of a variety of diseases including
cancer, and aberrant levels of modified nucleosides in RNA were revealed to be related to …

Magnetic particles (MPs) are the most widely used commercialized engineering particles,
which gained great success in various biological applications. Inspired by their intrinsic Fe …

Carboxylic metabolites are an important class of metabolites, which widely exist in mammals
with various types. Chemical isotope labeling liquid chromatography-mass spectrometry …