In mammalian blood plasma, serum albumin acts as a transport protein for free fatty acids,
other lipids and hydrophobic molecules including neurodegenerative peptides, and …

Repetitive mild traumatic brain injury (r-mTBI), commonly experienced by athletes and
military personnel, causes changes in multiple intracellular pathways, one of which involves …

Intraneuronal neurofibrillary tangles composed of Tau aggregates have been widely
accepted as an important pathological hallmark of Alzheimer's disease. Liquid-liquid phase …

A pathological hallmark of Alzheimer disease and other tauopathies is the formation of
neurofibrillary tangles mainly composed of bundles of fibrils formed by microtubule …

Traumatic brain Injury (TBI) is a significant cause of death and long-term disability for which
there are currently no effective pharmacological treatment options. In this study then, we …

Metal dyshomeostasis is a well-established consequence of neurodegenerative diseases
and traumatic brain injury. While the significance of metals continues to be uncovered in …

Traumatic brain injury (TBI) is complicated by a sudden and dramatic change in brain metal
levels, including iron (Fe), copper (Cu) and zinc (Zn). Specific 'metallo-pathological'features …

Zinc is a trace nutrient for the brain and a signal factor to serve for brain function. A portion of
zinc is released from glutamatergic (zincergic) neuron terminals in the brain. Synaptic Zn 2+ …

Aims: Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease
thought to be caused by repetitive traumatic brain injury (TBI) and subconcussive injuries …

Paramagnetic metal ion complexes, mostly based on gadolinium (Gd3+), have been used
for over 30 years as magnetic resonance imaging (MRI) contrast agents. Gd3+-based …