By virtue of its ability to regulate both protein turnover and non-proteolytic signalling
functions, ubiquitin protein conjugation has been implicated in the control of multiple cellular …

Epithelial ovarian cancer is the most lethal gynecological malignancy. Due to its lack of
symptoms, this disease is diagnosed at an advanced stage when the cancer has already …

Background: P53, EGFR and HER-2/neu are the most frequently studied molecular
biological parameters in epithelial ovarian cancer, but their prognostic impact is still …

Primary ovarian mucinous carcinomas of the intestinal type are uncommon and earlier
reports have included cases diagnosed according to older, less stringent, criteria (which …

In gynecological neoplasms, immunohistochemical (IHC) expression of p53 is generally an
accurate predictor of TP53 mutation status if correctly interpreted by the pathologist …

Background: The human kallikrein-related peptidase family consists of 15 genes. Twelve of
these genes are overexpressed in ovarian cancer and may represent potential markers for …

Objective The role of human papillomavirus (HPV) in the pathogenesis of ovarian cancer is
controversial, and conflicting results have been published. We conducted a systematic …

Objective An increasing body of evidence has suggested that epithelial ovarian cancer
(EOC) patients can broadly be divided into 2 groups on the basis of histopathologic …

Objective Abnormal expression of several biomarkers might predict disease prognosis and
response to chemotherapy in patients with epithelial ovarian cancer (EOC). However, the …

Borderline ovarian tumors show heterogeneity in clinical behavior. Most have excellent
prognosis, although a small percentage show recurrence or progressive disease, usually to …