Identification of potent anticancer agents with high selectivity and low toxicity remains on the
way to human health. Pyridazine featuring advantageous physicochemical properties and …

Bacterial resistance remains a significant threat and a leading cause of death worldwide,
despite massive attempts to control infections. In an effort to develop biologically active …

Antibiotic resistance is rapidly evolving at an alarming rate, posing a severe threat to
humanity. In an effort to develop compounds with antimicrobial activity, we synthesized a …

Abstract New phthalazone tethered 1, 2, 3-triazole derivatives 12–21 were synthesized
utilizing the Cu (I)-catalyzed click reactions of alkyne-functionalized phthalazone 1 with …

Antibiotic-resistant bacteria are emerging at an alarming rate, posing a potential threat to
human health. We synthesised alkyne-functionalised pyridines 3 and 4via alkylation of …

Over the past decades, antibiotic resistance has garnered considerable attention as a public
health concern. Therefore, it has become necessary to develop new generations of …

A series of mono-and bis-1, 2, 3-triazole-based molecular architectures were prepared in
excellent yields via the standard copper (I)-catalysed azide–alkyne cycloaddition (CuAAC) …

In spite of search for newer and effective antibacterial drugs, nature has paved way to
identify lead molecules from plants to treat chronic diseases. In an effort to develop …

In an attempt to improve the performance of biologically active anticancer agents, a novel
series of 1-substituent-4-(3, 4-dimethoxyphenyl)-1 H-1, 2, 3-triazole hybrids 10–16 were …

Abstract Various 2-phenyl-3, 6-pyridazinedione derivatives 4a-j, 5a-c, 6a, b, 7a-c, 8, 9, 10a-
d, and 11a-d, were effectively synthesized, and tested for their potential inhibition of …