Recent Developments and Biological Activities of N-Substituted Carbazole Derivatives: A Review

M Bashir, A Bano, AS Ijaz, BA Chaudhary - Molecules, 2015 - mdpi.com
Carbazoles represent an important class of heterocycles. These have been reported to
exhibit diverse biological activities such as antimicrobial, antitumor, antiepileptic …

Carbazole scaffolds in cancer therapy: a review from 2012 to 2018

S Issa, A Prandina, N Bedel, P Rongved… - Journal of enzyme …, 2019 - Taylor & Francis
For over half a century, the carbazole skeleton has been the key structural motif of many
biologically active compounds including natural and synthetic products. Carbazoles have …

Recent advancement of piperidine moiety in treatment of cancer-A review

P Goel, O Alam, MJ Naim, F Nawaz, M Iqbal… - European journal of …, 2018 - Elsevier
Piperidine is an important pharmacophore, a privileged scaffold and an excellent
heterocyclic system in the field of drug discovery which provides numerous opportunities in …

Escin reduces cell proliferation and induces apoptosis on glioma and lung adenocarcinoma cell lines

GA Çiftçi, A Işcan, M Kutlu - Cytotechnology, 2015 - Springer
Aesculus hippocastanum (the horse chestnut) seed extract has a wide variety of biochemical
and pharmacological effects including anti-inflammatory, antianalgesic, and antipyretic …

Recent synthetic strategies for the construction of functionalized carbazoles and their heterocyclic motifs enabled by Lewis acids

MP Kumar, G Mahantesh, P Amaladass… - RSC …, 2023 - pubs.rsc.org
This article demonstrates recent innovative cascade annulation methods for preparing
functionalized carbazoles and their related polyaromatic heterocyclic compounds enabled …

Current perspective of natural alkaloid carbazole and its derivatives as antitumor agents

MS Shaikh, R Karpoormath, N Thapliyal… - Anti-Cancer Agents …, 2015 - ingentaconnect.com
Throughout our evolution, the importance of natural products for medicine and health has
been increasing and it continues to be a key source of novel anticancer drugs, leads and …

Contributions of Chemical Content and Biological Activity to Plant Taxonomy Based on the Four Allium L. Taxa (Sect. Cupanioscordum ‐ Amaryllidaceae)

G Ekşi Bona, G Akalın Çiftçi, B Demirci… - Chemistry & …, 2023 - Wiley Online Library
Garlic and onions are used as food and for medicinal purposes worldwide. Allium L. species
are rich in bioactive organosulphur compounds that exhibit many biological activities like …

Progress and development of C-3, C-6, and N-9 positions substituted carbazole integrated molecular hybrid molecules as potential anticancer agents

PM Luthra, N Kumar - Mini Reviews in Medicinal Chemistry, 2021 - ingentaconnect.com
The carbazole skeleton, a key structural motif occurring naturally or chemically synthesized,
showed various biological activities. Molecular hybridization based on the combination of …

Synthesis and biological activity of pyrrolidine/piperidine substituted 3-amido-9-ethylcarbazole derivatives

S Sirin, H Duyar, B Aslım, Z Seferoğlu - Journal of Molecular Structure, 2021 - Elsevier
In this study, pyrrolidine/piperidine substituted 3-amido-9-ethylcarbazole derivatives were
synthesized and characterized by FT-IR, 1 H NMR, 13 C NMR spectroscopic and HRMS …

New thiazoline-tetralin derivatives and biological activity evaluation

G Turan-Zitouni, L Yurttaş, A Tabbi, G Akalın Çiftçi… - Molecules, 2018 - mdpi.com
In this study, novel N′-(3-cyclohexyl/phenyl-4-(substituted phenyl) thiazole-2 (3 H)-ylidene)-
2-[(5, 6, 7, 8-tetrahydronaphthalen-2-yl) oxy] acetohydrazide (4a–4k) derivatives were …