Carotenoid actions and their relation to health and disease

NI Krinsky, EJ Johnson - Molecular aspects of medicine, 2005 - Elsevier
Based on extensive epidemiological observation, fruits and vegetables that are a rich source
of carotenoids are thought to provide health benefits by decreasing the risk of various …

Tomato (Solanum lycopersicum) health components: from the seed to the consumer

M Dorais, DL Ehret, AP Papadopoulos - Phytochemistry Reviews, 2008 - Springer
It is widely accepted that a healthy diet is an important factor in preventing chronic diseases,
and in improving energy balance and weight management. Studies have shown strong …

Antioxidants in photosynthesis and human nutrition

B Demmig-Adams, WW Adams III - Science, 2002 - science.org
The harnessing of solar energy by photosynthesis depends on a safety valve that effectively
eliminates hazardous excess energy and prevents oxidative damage to the plant cells. Many …

Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines

NF Gloria, N Soares, C Brand, FL Oliveira… - Anticancer …, 2014 - ar.iiarjournals.org
Lycopene and beta-carotene are carotenoids widely distributed in fruits and vegetables, with
potential anticancer activity. Epidemiological trials rarely provide evidence for the …

Lutein and zeaxanthin and their potential roles in disease prevention

JD Ribaya-Mercado, JB Blumberg - Journal of the American …, 2004 - Taylor & Francis
Lutein and zeaxanthin are xanthophyll carotenoids found particularly in dark-green leafy
vegetables and in egg yolks. They are widely distributed in tissues and are the principal …

A review of natural and synthetic antioxidants important for health and longevity

M Wojcik, I Burzynska-Pedziwiatr… - Current Medicinal …, 2010 - ingentaconnect.com
Reactive oxygen species (ROS) generated in the presence of O2 by mitochondria,
phagocytic cells, peroxisomes, and cytochrome P450 enzymes under physiological …

Melatonin and cell death: differential actions on apoptosis in normal and cancer cells

RM Sainz, JC Mayo, C Rodriguez, DX Tan… - Cellular and Molecular …, 2003 - Springer
Melatonin is a natural compound synthesized by a variety of organs. It has been shown to
function as a cell-protective agent. Since 1994, when the first paper was published …

Antioxidant and anti-proliferative properties of lycopene

M Kelkel, M Schumacher, M Dicato… - Free radical …, 2011 - Taylor & Francis
The recent search for new anti-cancer drugs focuses more on natural compounds from the
regular human diet because these compounds rarely exhibit severe side-effects yet …

Pro-oxidant natural products as anticancer agents

C Martin-Cordero, A Jose Leon-Gonzalez… - Current drug …, 2012 - ingentaconnect.com
Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …

Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells

E Kotake-Nara, A Asai, A Nagao - Cancer letters, 2005 - Elsevier
Neoxanthin and fucoxanthin, which have the characteristic structure of 5, 6-monoepoxide
and an allenic bond, were previously found to reduce the viability of human prostate cancer …