The work of Katz and colleagues (Katz, 1969) provided an understanding of the main
modeof neurotransmitter release in the nervous system. Calcium entry into the presynaptic …

In the vertebrate retina, all photoreceptors hyperpolarize in response to light. In the outer
retina, at the bipolar cell level, a dual system is created from the cones forming the ON and …

This review compares the biological and physiological function of Sigma receptors [σRs] and
their potential therapeutic roles. Sigma receptors are widespread in the central nervous …

In addition to photoreceptors and neurons, glial cells (in particular Müller cells) contribute to
the removal and metabolization of neurotransmitters in the neural retina. This review …

Purpose Our objective was to comprehensively assess the nature and chronology of neural
remodeling in retinal degenerations triggered by light-induced retinal damage (LIRD) in …

An electron microscopic, double-labelling immunocytochemical procedure was used to
assess the level of fixed glutamate and glutamine in different cell profiles in ultrathin sections …

We survey the evidence for L-glutamate's role as the primary excitatory neurotransmitter of
vertebrate retinas. The physiological and molecular properties of glutamate receptors in the …

Diabetes is known to cause significant alterations in the retinal vasculature. Indeed, diabetic
retinopathy is the leading cause of blindness in those of working age. Considerable …

Purpose A connectome is a comprehensive description of synaptic connectivity for a neural
domain. Our goal was to produce a connectome data set for the inner plexiform layer of the …

Glutamate is the most abundant excitatory neurotransmitter in the vertebrate central nervous
system. It is widely assumed that neurons using this transmitter derive it from several …