Virus isoelectric point estimation: Theories and methods
Much of virus fate, both in the environment and in physical/chemical treatment, is dependent
on electrostatic interactions. Developing an accurate means of predicting virion isoelectric …
on electrostatic interactions. Developing an accurate means of predicting virion isoelectric …
Virus–receptor interactions: Structural insights for oncolytic virus development
N Jayawardena, LN Burga, JT Poirier… - Oncolytic …, 2019 - Taylor & Francis
Recent advancements in oncolytic virotherapy commend a special attention to developing
new strategies for targeting cancer cells with oncolytic viruses (OVs). Modifications of the …
new strategies for targeting cancer cells with oncolytic viruses (OVs). Modifications of the …
A human monoclonal antibody binds within the poliovirus receptor-binding site to neutralize all three serotypes
AJ Charnesky, JE Faust, H Lee, RD Puligedda… - Nature …, 2023 - nature.com
Global eradication of poliovirus remains elusive, and it is critical to develop next generation
vaccines and antivirals. In support of this goal, we map the epitope of human monoclonal …
vaccines and antivirals. In support of this goal, we map the epitope of human monoclonal …
Nectin-like interactions between poliovirus and its receptor trigger conformational changes associated with cell entry
M Strauss, DJ Filman, DM Belnap, N Cheng… - Journal of …, 2015 - Am Soc Microbiol
Poliovirus infection is initiated by attachment to a receptor on the cell surface called Pvr or
CD155. At physiological temperatures, the receptor catalyzes an irreversible expansion of …
CD155. At physiological temperatures, the receptor catalyzes an irreversible expansion of …
All-atom molecular dynamics calculation study of entire poliovirus empty capsids in solution
Small viruses that belong, for example, to the Picornaviridae, such as poliovirus and foot-
and-mouth disease virus, consist simply of capsid proteins and a single-stranded RNA …
and-mouth disease virus, consist simply of capsid proteins and a single-stranded RNA …
Design and molecular docking studies of {N1-[2-(amino)ethyl]ethane-1,2-diamine}-[tris(oxido)]-molybdenum(VI) complex as a potential antivirus drug: from synthesis …
S Kumar, M Choudhary - Journal of Coordination Chemistry, 2023 - Taylor & Francis
The aim of this study was to synthesize and examine the molecular docking of a Mo (VI)
complex [Mo (dien) O3](1),{N1-[2-(amino) ethyl] ethane-1, 2-diamine}-[tris (oxido)] …
complex [Mo (dien) O3](1),{N1-[2-(amino) ethyl] ethane-1, 2-diamine}-[tris (oxido)] …
Structural analysis of coxsackievirus A7 reveals conformational changes associated with uncoating
JJT Seitsonen, S Shakeel, P Susi… - Journal of …, 2012 - Am Soc Microbiol
ABSTRACT Coxsackievirus A7 (CAV7) is a rarely detected and poorly characterized
serotype of the Enterovirus species Human enterovirus A (HEV-A) within the Picornaviridae …
serotype of the Enterovirus species Human enterovirus A (HEV-A) within the Picornaviridae …
Evaluation and Use of In-Silico Structure-Based Epitope Prediction with Foot-and-Mouth Disease Virus
DW Borley, M Mahapatra, DJ Paton, RM Esnouf… - PloS one, 2013 - journals.plos.org
Understanding virus antigenicity is of fundamental importance for the development of better,
more cross-reactive vaccines. However, as far as we are aware, no systematic work has yet …
more cross-reactive vaccines. However, as far as we are aware, no systematic work has yet …
Structural basis of human parechovirus neutralization by human monoclonal antibodies
S Shakeel, BM Westerhuis, A Ora, G Koen… - Journal of …, 2015 - Am Soc Microbiol
Since it was first recognized in 2004 that human parechoviruses (HPeV) are a significant
cause of central nervous system and neonatal sepsis, their clinical importance, primarily in …
cause of central nervous system and neonatal sepsis, their clinical importance, primarily in …
Improved virus isoelectric point estimation by exclusion of known and predicted genome-binding regions
Knowledge of the isoelectric points (pIs) of viruses is beneficial for predicting virus behavior
in environmental transport and physical/chemical treatment applications. However, the …
in environmental transport and physical/chemical treatment applications. However, the …