Abstract The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal
transduction network in eukaryotic cells that promotes cell survival, cell growth, and cell …

Cancer is a severe public health issue that is a leading cause of mortality globally. It is also
an impediment to improving life expectancy worldwide. Furthermore, the global burden of …

Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …

Skin cancer is a global threat to the healthcare system and is estimated to incline
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …

Simple Summary The research outlined in this review paper discusses potential health
benefits associated with a diet enriched with tomatoes and tomato products. This includes …

Cellular metabolism is at the foundation of all biological activities. The catabolic processes
that support cellular bioenergetics and survival have been well studied. By contrast, how …

Abstract The phosphatidylinositol 3-kinase (PI3K)-Akt and the mammalian target of
rapamycin (mTOR) represent two vital intracellular signaling pathways, which are …

Abstract Objects Traumatic spinal cord injury (TSCI) causes neurological dysfunction below
the injured segment of the spinal cord, which significantly impacts the quality of life in …

Abstract N 6-methyladenosine (m6A) messenger RNA methylation is a gene regulatory
mechanism affecting cell differentiation and proliferation in development and cancer. To …

Abstract Phosphatidylinositol 3-kinases (PI3Ks) are crucial coordinators of intracellular
signalling in response to the extracellular stimulators. Hyperactivation of PI3K signalling …