Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …

Isothermal nucleic acid amplification techniques are used to detect a variety of molecules
such as RNAs, DNAs and proteins. When compared to the gold standard polymerase chain …

Genome sequencing of single cells has a variety of applications, including characterizing
difficult-to-culture microorganisms and identifying somatic mutations in single cells from …

Abstract Background Multiple Displacement Amplification (MDA) is a method used for
amplifying limiting DNA sources. The high molecular weight amplified DNA is ideal for DNA …

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, poses grave threats to both the
global economy and health. The predominant diagnostic screens in use for SARS-CoV-2 …

Paper-based biosensors are microfluidic analytical devices used for the detection of
biochemical substances. The unique properties of paper-based biosensors, including low …

False-positive results cause a major problem in nucleic acid amplification, and require
external blank/negative controls for every test. However, external controls usually have a …

Microbial ecology is a field that applies molecular techniques to analyze genes and
communities associated with a plethora of unique environments on this planet. In the past …

Intensively developed in the last few years, single-cell sequencing technologies now
present numerous advantages over traditional sequencing methods for solving the problems …

Recently developed techniques allow genomic DNA sequencing from single microbial cells
[Lasken RS: Single-cell genomic sequencing using multiple displacement amplification …