Diffusion-weighted MRI in the body: applications and challenges in oncology

DM Koh, DJ Collins - American Journal of Roentgenology, 2007 - Am Roentgen Ray Soc
OBJECTIVE. In this article, we present the basic principles of diffusion-weighted imaging
(DWI) that can aid radiologists in the qualitative and quantitative interpretation of DW …

Inflammation and necrosis promote tumour growth

J Vakkila, MT Lotze - Nature Reviews Immunology, 2004 - nature.com
In children, cancer probably arises from a combination of inherited genetic mutations and
genetic alterations that are acquired during the rapid cellular expansion that occurs during …

Rectal cancer: assessment of neoadjuvant chemoradiation outcome based on radiomics of multiparametric MRI

K Nie, L Shi, Q Chen, X Hu, SK Jabbour, N Yue… - Clinical cancer …, 2016 - AACR
Purpose: To evaluate multiparametric MRI features in predicting pathologic response after
preoperative chemoradiation therapy (CRT) for locally advanced rectal cancer (LARC) …

Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations

AR Padhani, G Liu, D Mu-Koh, TL Chenevert… - Neoplasia, 2009 - Elsevier
Abstract On May 3, 2008, a National Cancer Institute (NCI)-sponsored open consensus
conference was held in Toronto, Ontario, Canada, during the 2008 International Society for …

Diffusion-weighted MRI for selection of complete responders after chemoradiation for locally advanced rectal cancer: a multicenter study

DMJ Lambregts, V Vandecaveye, B Barbaro… - Annals of surgical …, 2011 - Springer
Abstract Purpose In 10–24% of patients with rectal cancer who are treated with neoadjuvant
chemoradiation, no residual tumor is found after surgery (ypT0). When accurately selected …

Diffusion-weighted imaging in the abdomen and pelvis: concepts and applications

A Qayyum - Radiographics, 2009 - pubs.rsna.org
Diffusion-weighted magnetic resonance (MR) imaging allows the detection of focal solid and
cystic lesions in the abdomen and pelvis and, if pitfalls are to be avoided, is most effectively …

Locally advanced rectal cancer: added value of diffusion-weighted MR imaging in the evaluation of tumor response to neoadjuvant chemo-and radiation therapy

SH Kim, JM Lee, SH Hong, GH Kim, JY Lee, JK Han… - Radiology, 2009 - pubs.rsna.org
Purpose To investigate the added value of diffusion-weighted (DW) magnetic resonance
(MR) imaging in the evaluation of complete response (CR) to neoadjuvant combined …

Technology insight: water diffusion MRI—a potential new biomarker of response to cancer therapy

DM Patterson, AR Padhani, DJ Collins - Nature clinical practice …, 2008 - nature.com
Abstract Diffusion-weighted MRI (DW-MRI) is a functional imaging technique that displays
information about the extent and direction of random water motion in tissues. Water …

Diffusion-weighted imaging in rectal cancer: current applications and future perspectives

NW Schurink, DMJ Lambregts… - The British journal of …, 2019 - academic.oup.com
This review summarizes current applications and clinical utility of diffusion-weighted imaging
(DWI) for rectal cancer and in addition provides a brief overview of more recent …

Diffusion changes precede size reduction in neoadjuvant treatment of breast cancer

MD Pickles, P Gibbs, M Lowry, LW Turnbull - Magnetic resonance imaging, 2006 - Elsevier
Traditionally, tumor response has been assessed via tumor size measurements during the
course of a treatment. However, changes in these morphologically based measures occur …