Important roles of the Ca2+-sensing receptor in vascular health and disease

Y Guo, X Yang, J He, J Liu, S Yang, H Dong - Life sciences, 2018 - Elsevier
Abstract Ca 2+-sensing receptor (CaSR), a member of G protein-coupled receptor family, is
widely expressed in the vascular system, including perivascular neurons, vascular …

[HTML][HTML] Family C G-protein-coupled receptors in Alzheimer's disease and therapeutic implications

I Dal Prà, U Armato, A Chiarini - Frontiers in pharmacology, 2019 - frontiersin.org
Alzheimer's disease (AD), particularly its sporadic or late-onset form (SAD/LOAD), is the
most prevalent (96–98% of cases) neurodegenerative dementia in aged people. AD's …

[HTML][HTML] Alzheimer's Disease and Its Possible Evolutionary Origin: Hypothesis

JF Whitfield, K Rennie, B Chakravarthy - Cells, 2023 - mdpi.com
The enormous, 2–3-million-year evolutionary expansion of hominin neocortices to the
current enormity enabled humans to take over the planet. However, there appears to have …

[HTML][HTML] Calcilytic NPS 2143 Reduces Amyloid Secretion and Increases sAβPP α Release from PSEN1 Mutant iPSC-Derived Neurons

M Lo Giudice, B Mihalik, Z Turi… - Journal of …, 2019 - content.iospress.com
Despite numerous efforts and studies over the last three decades, Alzheimer's disease (AD)
remains a disorder not fully understood and incurable so far. Development of induced …

Astrocytes' role in Alzheimer's disease neurodegeneration

I Dal Prà, U Armato, A Chiarini - Astrocyte-Physiology and …, 2018 - books.google.com
Central nervous system (CNS) astrocytes are glial cells performing crucial tasks
encompassing energy metabolism, neurotransmission, ion and water stable levels, and …

[PDF][PDF] Alzheimer's Disease and Its Possible Evolutionary Origin: Hypothesis. Cells 2023, 12, 1618

JF Whitfield, K Rennie, B Chakravarthy - 2023 - academia.edu
The enormous, 2–3-million-year evolutionary expansion of hominin neocortices to the
current enormity enabled humans to take over the planet. However, there appears to have …

Alzheimer's Disease Neuroprotection: Associated Receptors

AB Câmara - Neuroprotection-New Approaches and Prospects, 2020 - books.google.com
Research with humans and animals has been developed over the past few years to identify
receptors involved in Alzheimer's disease, aiming at a better understanding of the …

[PDF][PDF] The Role of Astrocytes in Astrocytes Alzheimer's Disease

I MAVROUDIS, F PETRIDIS… - 2020 - aos.ro
Astrocytes are highly specialized glial cells and play a crucial role in neuronal functionality
and brain functional integrity. Although research on Alzheimer's disease has been …