Inflammation, although first characterized by Cornelius Celsus, a physician in first Century
Rome, it was Rudolf Virchow, a German physician in nineteenth century who suggested a …

Vitex negundo L.(Verbenaceae) is a hardy plant, flourishing mainly in the Indian
subcontinent. All parts of the plant, from root to fruit, possess a multitude of phytochemical …

Two pentacyclic triterpenoids, betulinic acid (3β‐hydroxylup‐20‐(29)‐en‐28‐oic acid)(3),
and ursolic acid (2β‐hydroxyurs‐12‐en‐28‐oic acid)(4), were isolated for the first time from …

Xanthine oxidase inhibitory activity was assayed from six species belonging to different
families traditionally used for the treatment of gout and related symptoms by indigenous …

Flavonoids are ubiquitous in photosynthesizing cells and are common part of human diet.
For centuries, preparations containing these compounds as the principal physiologically …

Ethnopharmacological relevance Tharu community is the largest primitive indigenous
community of the Uttarakhand, India. In this article we have scientifically enumerated …

The search for new anti-inflammatory agents is challenging due to the complexity of the
inflammatory process and its role in host defense. Over the past few decades, a significant …

Natural products are rich in several potent bioactive compounds, targeting complex network
of proteins involved in various diseases. Vitex negundo (VN), commonly known as “chaste …

Essential oils from fresh leaves, flowers and dried fruits of Vitex negundo were obtained by
hydrodistillation. Using Soxhlet extractor five successive extracts from dried and powdered …

Objective: To evaluate the analgesic and antiinflammatory activities of hydroalcoholic extract
of Vitex negundo leaves and to elucidate possible mechanism (s) of its pharmacological …