The adaptive response of connective tissue to loading requires increased synthesis and
turnover of matrix proteins, with special emphasis on collagen. Collagen formation and …

Owing to limited self‐healing capacity, tendon ruptures and healing remain major orthopedic
challenges. Increasing evidence suggests that post‐traumatic inflammatory responses, and …

Injured tendons heal slowly and often result in the formation of mechanically and functionally
inferior fibrotic scar tissue or fibrous adhesions. This study investigated the use of tendon …

Proper cell source is one of the key issues for tendon engineering. Our previous study
showed that dermal fibroblasts could be used to successfully engineer tendon in vivo and …

The extracellular matrix (ECM) of skeletal muscle and tendon is composed of different types
of collagen molecules that play important roles in the transmission of forces throughout the …

Tendon‐derived stem cells (TDSCs) play a vital role in repair of rotator cuff tear injuries by
secreting paracrine proteins that regulate resident cell functions. Secreted exosomes may …

Background/Aims: Tendon injuries are common, difficult to cure and usually healed with
fibrosis and scar tissue. The aim of this study was to evaluate tendon derived stem cells …

Tendon/ligament injuries are very common in sports and other rigorous activities. Tendons
regenerate and repair slowly and inefficiently in vivo after injury. The limited ability of tendon …

Repaired Achilles tendons typically take weeks before they are strong enough to handle
physiological loads. Gene therapy is a promising treatment for Achilles tendon defects. The …

Purpose Results of in vitro cell models are commonly used to promote new therapies (eg,
platelet-rich plasma), and clinicians have to be aware of the specific limitations of such …