Dynamic Nuclear Polarization Illuminates Key Protein–Lipid Interactions in the Native Bacterial Cell Envelope
Elucidating the structure and interactions of proteins in native environments is a fundamental
goal of structural biology. Nuclear magnetic resonance (NMR) spectroscopy is well suited for …
goal of structural biology. Nuclear magnetic resonance (NMR) spectroscopy is well suited for …
A Comparative Study of Nitroxide‐Based Biradicals for Dynamic Nuclear Polarization in Cellular Environments
BE Ackermann, BJ Lim, N Elathram… - …, 2022 - Wiley Online Library
Dynamic nuclear polarization (DNP) is a powerful tool to enhance the NMR signals of
molecules by transferring polarization from unpaired electron spins to nuclei through …
molecules by transferring polarization from unpaired electron spins to nuclei through …
Solid-state NMR MAS CryoProbe enables structural studies of human blood protein vitronectin bound to hydroxyapatite
The low sensitivity of nuclear magnetic resonance (NMR) is a major bottleneck for studying
biomolecular structures of complex biomolecular assemblies. Cryogenically cooled probe …
biomolecular structures of complex biomolecular assemblies. Cryogenically cooled probe …
Interaction between Yersinia pestis Ail Outer Membrane Protein and the C-Terminal Domain of Human Vitronectin
L Vasseur, F Barbault, A Monari - The Journal of Physical …, 2024 - ACS Publications
Yersinia pestis, the causative agent of plague, is capable of evading the human immune
system response by recruiting the plasma circulating vitronectin proteins, which act as a …
system response by recruiting the plasma circulating vitronectin proteins, which act as a …
Interplays of mutations in waaA, cmk, and ail contribute to phage resistance in Yersinia pestis
L Xiao, Z Qi, K Song, R Lv, R Chen, H Zhao… - Frontiers in Cellular …, 2023 - frontiersin.org
Plague caused by Yersinia pestis remains a public health threat worldwide. Because
multidrug-resistant Y. pestis strains have been found in both humans and animals, phage …
multidrug-resistant Y. pestis strains have been found in both humans and animals, phage …
Membranes, Minerals and Magnets: Application of NMR Spectroscopy to Biological Interfaces
Nature has evolved sophisticated mechanisms of producing biomolecular structures that
compartmentalize various biochemical and cellular environments. Biological membranes …
compartmentalize various biochemical and cellular environments. Biological membranes …
Structure-and Dynamics-guided Drug Development Using NMR and its Application to Diverse Pharmaceutical Modalities
K Takeuchi - 2022 - books.rsc.org
The unique strength of solution-state nuclear magnetic resonance (NMR) is to contribute not
only to determine high-resolution structures of macromolecules but also to provide …
only to determine high-resolution structures of macromolecules but also to provide …