The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications
E Campo, SH Swerdlow, NL Harris… - Blood, The Journal …, 2011 - ashpublications.org
Abstract The World Health Organization classification of lymphoid neoplasms updated in
2008 represents a worldwide consensus on the diagnosis of these tumors and is based on …
2008 represents a worldwide consensus on the diagnosis of these tumors and is based on …
The anaplastic lymphoma kinase in the pathogenesis of cancer
Tyrosine kinases are involved in the pathogenesis of most cancers. However, few tyrosine
kinases have been shown to have a well-defined pathogenetic role in lymphomas. The …
kinases have been shown to have a well-defined pathogenetic role in lymphomas. The …
Methionine is a metabolic dependency of tumor-initiating cells
Understanding cellular metabolism holds immense potential for developing new classes of
therapeutics that target metabolic pathways in cancer. Metabolic pathways are altered in …
therapeutics that target metabolic pathways in cancer. Metabolic pathways are altered in …
Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma
J Iqbal, G Wright, C Wang, A Rosenwald… - Blood, The Journal …, 2014 - ashpublications.org
Peripheral T-cell lymphoma (PTCL) encompasses a heterogeneous group of neoplasms
with generally poor clinical outcome. Currently 50% of PTCL cases are not classifiable …
with generally poor clinical outcome. Currently 50% of PTCL cases are not classifiable …
A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma
The molecular mechanisms underlying angioimmunoblastic T cell lymphoma (AITL), a
common type of mature T cell lymphoma of poor prognosis, are largely unknown. Here we …
common type of mature T cell lymphoma of poor prognosis, are largely unknown. Here we …
Protein disulfide isomerase: a promising target for cancer therapy
S Xu, S Sankar, N Neamati - Drug discovery today, 2014 - Elsevier
Highlights•PDI is an important oxidase, reductase, isomerase and molecular
chaperone.•PDI expression is up-regulated in select types of cancers.•Silencing PDI results …
chaperone.•PDI expression is up-regulated in select types of cancers.•Silencing PDI results …
Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma
J Iqbal, DD Weisenburger, TC Greiner… - Blood, The Journal …, 2010 - ashpublications.org
Peripheral T-cell lymphoma (PTCL) is often challenging to diagnose and classify. Gene
expression profiling was performed on 144 cases of PTCL and natural killer cell lymphoma …
expression profiling was performed on 144 cases of PTCL and natural killer cell lymphoma …
Nutrition and carcinogenesis
AR Collins, LR Ferguson - Mutation Research/Fundamental and Molecular …, 2004 - Elsevier
Traditional views of nutritional carcinogenesis depend on the identification of exogenous
carcinogens as major risk factors. As our understanding evolves, it is clear that the pattern of …
carcinogens as major risk factors. As our understanding evolves, it is clear that the pattern of …
Peripheral T-cell lymphoma
FM Foss, PL Zinzani, JM Vose… - Blood, The Journal …, 2011 - ashpublications.org
Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of clinically aggressive
diseases associated with poor outcome. Studies that focus specifically on PTCL are …
diseases associated with poor outcome. Studies that focus specifically on PTCL are …
[HTML][HTML] Voltage-gated calcium channels: Novel targets for cancer therapy
Voltage-gated calcium channels (VGCCs) comprise five subtypes: The L‑type; R‑type; N‑
type; P/Q‑type; and T‑type, which are encoded by α1 subunit genes. Calcium ion channels …
type; P/Q‑type; and T‑type, which are encoded by α1 subunit genes. Calcium ion channels …