The international society of RNA nanotechnology and nanomedicine (ISRNN): the present and future of the burgeoning field

M Chandler, B Johnson, E Khisamutdinov… - ACS …, 2021 - ACS Publications
The International Society of RNA Nanotechnology and Nanomedicine (ISRNN) hosts an
annual meeting series focused on presenting the latest research achievements involving …

Synthetic biology of small RNAs and riboswitches

JK Villa, Y Su, LM Contreras… - Microbiology …, 2018 - Am Soc Microbiol
In bacteria and archaea, small RNAs (sRNAs) regulate complex networks through antisense
interactions with target mRNAs in trans, and riboswitches regulate gene expression in cis …

CsrA selectively modulates sRNA-mRNA regulator outcomes

AM Rojano-Nisimura, TR Simmons… - Frontiers in Molecular …, 2023 - frontiersin.org
Post-transcriptional regulation, by small RNAs (sRNAs) as well as the global Carbon
Storage Regulator A (CsrA) protein, play critical roles in bacterial metabolic control and …

Integrative FourD omics approach profiles the target network of the carbon storage regulatory system

SW Sowa, G Gelderman, AN Leistra… - Nucleic acids …, 2017 - academic.oup.com
Multi-target regulators represent a largely untapped area for metabolic engineering and anti-
bacterial development. These regulators are complex to characterize because they often act …

Sensing of biomolecular interactions using fluorescence complementing systems in living cells

XE Zhang, Z Cui, D Wang - Biosensors and Bioelectronics, 2016 - Elsevier
Sensing biomolecule interactions in living cells allows for a deeper understanding of the
mechanisms governing biological processes, and has increasing significance for …

Applications of protein fragment complementation assays for analyzing biomolecular interactions and biochemical networks in living cells

P Li, L Wang, L Di - Journal of proteome research, 2019 - ACS Publications
Protein–protein interactions (PPIs) are indispensable for the dynamic assembly of
multiprotein complexes that are central players of nearly all of the intracellular biological …

A canonical biophysical model of the CsrA global regulator suggests flexible regulator-target interactions

AN Leistra, G Gelderman, SW Sowa, A Moon-Walker… - Scientific reports, 2018 - nature.com
Bacterial global post-transcriptional regulators execute hundreds of interactions with targets
that display varying molecular features while retaining specificity. Herein, we develop …

A bacterial three-hybrid assay detects Escherichia coli Hfq–sRNA interactions in vivo

KE Berry, A Hochschild - Nucleic acids research, 2018 - academic.oup.com
The interaction of RNA molecules with proteins is a critical aspect of gene regulation across
all domains of life. Here, we report the development of a bacterial three-hybrid (B3H) assay …

[HTML][HTML] CsrA shows selective regulation of sRNA-mRNA networks

AM Rojano-Nisimura, TR Simmons, AN Leistra… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Post-transcriptional regulation, by small RNAs (sRNAs) as well as the global Carbon
Storage Regulator A (CsrA) protein, play critical roles in bacterial metabolic control and …

Slowing translation between protein domains by increasing affinity between mRNAs and the ribosomal anti-Shine–Dalgarno sequence improves solubility

KA Vasquez, TA Hatridge, NC Curtis… - ACS synthetic …, 2016 - ACS Publications
Recent studies have demonstrated that effective protein production requires coordination of
multiple cotranslational cellular processes, which are heavily affected by translation timing …