Effectiveness of zebrafish models in understanding human diseases—A review of models

M Adhish, I Manjubala - Heliyon, 2023 - cell.com
Understanding the detailed mechanism behind every human disease, disorder, defect, and
deficiency is a daunting task concerning the clinical diagnostic tools for patients. Hence, a …

Zebrafish models of cancer—new insights on modeling human cancer in a non-mammalian vertebrate

M Hason, P Bartůněk - Genes, 2019 - mdpi.com
Zebrafish (Danio rerio) is a valuable non-mammalian vertebrate model widely used to study
development and disease, including more recently cancer. The evolutionary conservation of …

[HTML][HTML] Novel biological insights in T-cell acute lymphoblastic leukemia

K Durinck, S Goossens, S Peirs, A Wallaert… - Experimental …, 2015 - Elsevier
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of blood cancer that
accounts for about 15% of pediatric and 25% of adult acute lymphoblastic leukemia (ALL) …

Aberrant signaling pathways in T-cell acute lymphoblastic leukemia

D Bongiovanni, V Saccomani, E Piovan - International journal of …, 2017 - mdpi.com
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease caused by the
malignant transformation of immature progenitors primed towards T-cell development …

[PDF][PDF] Cytokine signaling in tumor progression

M Lee, I Rhee - Immune network, 2017 - synapse.koreamed.org
Cytokines are molecules that play critical roles in the regulation of a wide range of normal
functions leading to cellular proliferation, differentiation and survival, as well as in …

Zebrafish-based platform for emerging bio-contaminants and virus inactivation research

P Patel, A Nandi, SK Verma, N Kaushik, M Suar… - Science of The Total …, 2023 - Elsevier
Emerging bio-contaminants such as viruses have affected health and environment settings
of every country. Viruses are the minuscule entities resulting in severe contagious diseases …

Genetic engineering of zebrafish in cancer research

L Raby, P Völkel, X Le Bourhis, PO Angrand - Cancers, 2020 - mdpi.com
Zebrafish (Danio rerio) is an excellent model to study a wide diversity of human cancers. In
this review, we provide an overview of the genetic and reverse genetic toolbox allowing the …

Zebrafish as a model for leukemia and other hematopoietic disorders

P Rasighaemi, F Basheer, C Liongue… - Journal of hematology & …, 2015 - Springer
Zebrafish is an established model for the study of vertebrate development, and is especially
amenable for investigating hematopoiesis, where there is strong conservation of key …

Zebrafish as a genetic model in pre-clinical drug testing and screening

Y Gibert, MC Trengove, AC Ward - Current medicinal chemistry, 2013 - ingentaconnect.com
The traditional drug discovery pipeline for the identification and development of compounds
that selectively target specific molecules to ameliorate disease remains a major focus for …

The Zebrafish model in dermatology: an update for clinicians

I Russo, E Sartor, L Fagotto, A Colombo, N Tiso… - Discover Oncology, 2022 - Springer
Recently, the zebrafish has been established as one of the most important model organisms
for medical research. Several studies have proved that there is a high level of similarity …