Isocyanoacetate derivatives: synthesis, reactivity, and application
AV Gulevich, AG Zhdanko, RVA Orru… - Chemical …, 2010 - ACS Publications
Isocyanide (isonitrile) chemistry began in 1859 when Lieke obtained the first compound of
this type. 1 In 1958, isocyanides became generally available by dehydration of formamides …
this type. 1 In 1958, isocyanides became generally available by dehydration of formamides …
Catalytic asymmetric synthesis of α-amino acids
C Najera, JM Sansano - Chemical reviews, 2007 - ACS Publications
Proteinogenic and non-proteinogenic R-amino acids (R-AAs) constitute one of the five most
important families of natural products1 and are essential molecules in many scientific areas …
important families of natural products1 and are essential molecules in many scientific areas …
Rationally designed peptides and peptidomimetics as inhibitors of amyloid-β (Aβ) aggregation: Potential therapeutics of Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease with no clinically
accepted treatment to cure or halt its progression. The worldwide effort to develop peptide …
accepted treatment to cure or halt its progression. The worldwide effort to develop peptide …
Metathesis in the synthesis of aromatic compounds
WAL van Otterlo, CB De Koning - Chemical reviews, 2009 - ACS Publications
The importance of aromatic structures in organic chemistry can never be underestimated.
Nature uses compounds containing aromatic or heteroaromatic nuclei extensively as the …
Nature uses compounds containing aromatic or heteroaromatic nuclei extensively as the …
Recent progress on the stereoselective synthesis of acyclic quaternary α-amino acids
C Cativiela, MD Díaz-de-Villegas - Tetrahedron: Asymmetry, 2007 - Elsevier
Recent progress on the stereoselective synthesis of acyclic quaternary α-amino acids -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …
Transition metal catalyzed [2+ 2+ 2] cycloaddition and application in organic synthesis
S Kotha, E Brahmachary, K Lahiri - European journal of organic …, 2005 - Wiley Online Library
Abstract The [2+ 2+ 2] cycloaddition strategy is complementary to the well known Diels–
Alder reaction for the generation of polycyclic compounds. This [2+ 2+ 2] approach is atom …
Alder reaction for the generation of polycyclic compounds. This [2+ 2+ 2] approach is atom …
Domino coupling relay approach to polycyclic pyrrole-2-carboxylates
Y Yamamoto, H Hayashi, T Saigoku… - Journal of the …, 2005 - ACS Publications
CuBr2-catalyzed three-component coupling of N-benzylallylamine, ethyl glyoxalate, and
terminal alkynes afforded glycine-tethered 1, 6-enynes, which were further transformed into …
terminal alkynes afforded glycine-tethered 1, 6-enynes, which were further transformed into …
Design and synthesis of spirocycles
In this account we disclose a variety of simple strategies demonstrated in our laboratory in
the last two decades for the assembly of diverse and intricate molecular frameworks …
the last two decades for the assembly of diverse and intricate molecular frameworks …
Diversity-oriented approaches to unusual α-amino acids and peptides: step economy, atom economy, redox economy, and beyond
Here we describe several useful strategies to a variety of unusual α-amino acid derivatives
and peptides based on “building block” approach. These building blocks are suitable for …
and peptides based on “building block” approach. These building blocks are suitable for …