Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms.
The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by …

Living organisms such as bacteria are often exposed to continuous changes in the nutrient
availability in nature. Therefore, bacteria must constantly monitor the environmental …

Experimental characterization of membrane proteins often requires solubilization. A recent
approach is to use styrene-maleic acid (SMA) copolymers to isolate membrane proteins in …

Background Sigma-54 is a central regulator in many pathogenic bacteria and has been
linked to a multitude of cellular processes like nitrogen assimilation and important functional …

To overcome the deleterious effects of acid stress, Lactobacillus delbrueckii subsp.
bulgaricus (L. bulgaricus) elicits an adaptive response to acid stress. In this study …

Metabolic heterogeneity between individual cells of a population harbors significant
challenges for fundamental and applied research. Identifying metabolic heterogeneity and …

Assessing gene expression noise in order to obtain mechanistic insights requires accurate
quantification of gene expression on many individual cells over a large dynamic range. We …

Elucidation of the energetic principles of binding affinity and specificity is a central task in
many branches of current sciences: biology, medicine, pharmacology, chemistry, material …

Bacteria regulate cell physiology in response to extra‐and intracellular cues. Recent work
showed that metabolic fluxes are reported by specific metabolites, whose concentrations …

The SorC family of transcriptional regulators plays a crucial role in controlling the
carbohydrate metabolism and quorum sensing. We employed an integrative approach …