A novel approach to vaccination against cancer is to exploit dendritic cells (DCs) as 'nature's
adjuvants' and actively immunize cancer patients with a sample of their own DCs primed …

The transfusion of T cells, also called adoptive T cell therapy, is an effective treatment for
viral infections and has induced regression of cancer in early-stage clinical trials. However …

The use of peptide–human histocompatibility leukocyte antigen (HLA) class I tetrameric
complexes to identify antigen-specific CD8+ T cells has provided a major development in …

Human cytomegalovirus (HCMV) infection is largely asymptomatic in the immunocompetent
host, but remains a major cause of morbidity in immunosuppressed individuals. Using the …

Deregulation of signaling pathways is a hallmark of malignant transformation. Signaling-
associated phosphoproteins can be degraded to generate cancer-specific phosphopeptides …

In situ immune infiltrates in lesional, perilesional, and nonlesional skin biopsies from
patients with vitiligo were analyzed by immunohistochemistry and compared with immune …

Recently developed major histocompatibility complex (MHC) multimer technologies allow
visualization and isolation of antigen-specific T cells. However, functional analysis and in …

The development of fluorochrome‐conjugated peptide–major histocompatibility complex
(pMHC) multimers in conjunction with continuing advances in flow cytometry has …

Vitiligo is a disease of the skin characterized by the appearance of white spots. Significant
progress has been made in understanding vitiligo pathogenesis over the past 30 years, but …

Expression of NY-ESO-1 in a high proportion of different human tumors makes this protein a
very attractive vaccine target. NY-ESO-1 peptides, recognized by HLA-A2-restricted CTL …