[HTML][HTML] The role of wild-type tau in Alzheimer's disease and related tauopathies
CH Lo, JN Sachs - Journal of Life Sciences (Westlake Village, Calif …, 2020 - ncbi.nlm.nih.gov
Tau oligomers have recently emerged as the principal toxic species in Alzheimer's disease
(AD) and tauopathies. Tau oligomers are spontaneously self-assembled soluble tau proteins …
(AD) and tauopathies. Tau oligomers are spontaneously self-assembled soluble tau proteins …
Tau acetylation at K280 regulates tau phosphorylation
MS Kim, YS Mun, SE Lee, WY Cho… - International Journal …, 2023 - Taylor & Francis
Purpose/aim of the study Accumulation of hyperphosphorylated tau is a key pathological
finding of Alzheimer's disease. Recently, acetylation of tau is emerging as another key …
finding of Alzheimer's disease. Recently, acetylation of tau is emerging as another key …
Molecular mechanism of amyloidogenicity and neurotoxicity of a pro-aggregated tau mutant in the presence of histidine tautomerism via replica-exchange simulation
S Chatterjee, A Salimi, JY Lee - Physical Chemistry Chemical Physics, 2021 - pubs.rsc.org
The accumulation of ΔK280 tau mutant resulting in neurotoxic oligomeric aggregates is an
important but yet mysterious procedure in Alzheimer's disease (AD) development. Recently …
important but yet mysterious procedure in Alzheimer's disease (AD) development. Recently …
Molecular Insights into the Differential Effects of Acetylation on the Aggregation of Tau Microtubule-Binding Repeats
Aggregation of tau protein into intracellular fibrillary inclusions is characterized as the
hallmark of tauopathies, including Alzheimer's disease and chronic traumatic …
hallmark of tauopathies, including Alzheimer's disease and chronic traumatic …
Macrocyclic peptides derived from AcPHF6* and AcPHF6 to selectively modulate the Tau aggregation
Ten macrocyclic peptides, each comprising 14 amino acids, were designed and synthesized
based on the Tau aggregation model hexapeptides AcPHF6* and AcPHF6. The design took …
based on the Tau aggregation model hexapeptides AcPHF6* and AcPHF6. The design took …
Novel ultrasensitive immunoassay for the selective quantification of tau oligomers and related soluble aggregates
T Islam, H Kvartsberg, A Sehrawat… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Tau aggregation into paired helical filaments and neurofibrillary tangles is
characteristic of Alzheimer's disease (AD) and related disorders. However, biochemical …
characteristic of Alzheimer's disease (AD) and related disorders. However, biochemical …
[引用][C] The cross-talk between ApoE and Tau protein in Alzheimer's disease
S Chinnathambi, M Kumarappan, M Chandrashekar - 2024 - Elsevier
[引用][C] Lipid role in synapse and nuclear envelope-associated endocytic pathways in Tauopathy
S Chinnathambi, A Adithyan, M Chandrashekar - 2024 - Elsevier