[HTML][HTML] Recent advances in data-and knowledge-driven approaches to explore primary microbial metabolism

BJ Bartmanski, M Rocha… - Current Opinion in …, 2023 - Elsevier
With the rapid progress in metabolomics and sequencing technologies, more data on the
metabolome of single microbes and their communities become available, revealing the …

The potential antipyretic mechanism of ellagic acid with brain metabolomics using rats with yeast-induced fever

F Xie, L Xu, H Zhu, Y Chen, Y Li, L Nong, Y Zeng… - Molecules, 2022 - mdpi.com
Fever is caused by an increase in the heat production process when the body is under the
action of a heat source or the dysfunction of the temperature center. Ellagic acid (EA) is a …

Metabolomics analysis highlights Yashtimadhu (Glycyrrhiza glabra L.)mediated neuroprotection in a rotenone‐induced cellular model of Parkinson's disease by …

G Karthikkeyan, SK Behera, SS Upadhyay… - Phytotherapy …, 2022 - Wiley Online Library
Parkinson's disease (PD) is an age‐associated progressive neurodegenerative movement
disorder, and its management strategies are known to cause complications with prolonged …

Role of Hemigraphis alternata in wound healing: metabolomic profiling and molecular insights into mechanisms

R Devasahayam Arokia Balaya, A Palollathil… - Scientific Reports, 2024 - nature.com
Abstract Hemigraphis alternata (H. alternata), commonly known as Red Flame Ivy, is widely
recognized for its wound healing capabilities. However, the pharmacologically active plant …

Rifampicin-Mediated Metabolic Changes in Mycobacterium tuberculosis

SD Yelamanchi, A Mishra, SK Behra, G Karthikkeyan… - Metabolites, 2022 - mdpi.com
Mycobacterium tuberculosis (Mtb) is considered to be a devastating pathogen worldwide,
affecting millions of people globally. Several drugs targeting distinct pathways are utilized for …

Comparative Metabolomics and Network Pharmacology Analysis Reveal Shared Neuroprotective Mechanisms of Bacopa monnieri (L.) Wettst and Centella asiatica (L …

SS Parate, SS Upadhyay, G Karthikkeyan… - Molecular …, 2024 - Springer
Bacopa monnieri (L.) Wettst and Centella asiatica (L.) Urb., two nootropics, are recognized
in Indian Ayurvedic texts. Studies have attempted to understand their action as memory …

Metabolite Dysregulation by Pranlukast in Mycobacterium tuberculosis

SD Yelamanchi, ST Arun Kumar, A Mishra… - Molecules, 2022 - mdpi.com
Mycobacterium tuberculosis has been infecting millions of people worldwide over the years,
causing tuberculosis. Drugs targeting distinct cellular mechanisms including synthesis of the …

Susceptibility of rice crop to salt threat: proteomic, metabolomic, and physiological inspections

M Arefian, TSK Prasad - Journal of Proteome Research, 2022 - ACS Publications
Rice is a staple food crop worldwide; however, salinity stress is estimated to reduce its
global production by 50%. Knowledge about initial molecular signaling and proteins …

Metabolite profiling reveals overexpression of the global regulator, MoLAEA leads to increased synthesis of metabolites in Magnaporthe oryzae

P Subba, P Saha, G Karthikkeyan… - Journal of Applied …, 2022 - academic.oup.com
Aims To study the altered metabolic pathways and metabolites produced in overexpression
and knockdown mutants of a global regulator named MoLAEA, which was recently found to …

[HTML][HTML] From LC-MS/MS metabolomics profiling of Kanchanara Guggulu to molecular docking and dynamics simulation of quercetin pentaacetate with aldose …

SK Behera, PK Modi, G Karthikkeyan, SK Pervaje… - …, 2021 - ncbi.nlm.nih.gov
Kanchanara Guggulu (KG) is an important traditional medicine that is prescribed by the
Ayurveda physicians for the treatment of swellings in various organs such as the thyroid, and …