Membranes are flexible barriers that surround the cell and its compartments. To execute vital
functions such as locomotion or receptor turnover, cells need to control the shapes of their …

A mechanistic understanding of signaling networks requires identification and analysis of
phosphorylation sites. Mass spectrometry offers a rapid and highly sensitive approach to …

Animal cells undergo dramatic changes in shape, mechanics and polarity as they progress
through the different stages of cell division. These changes begin at mitotic entry, with cell …

The contractile ring is essential for cytokinesis in most fungal and animal cells. In fission
yeast, cytokinesis nodes are precursors of the contractile ring and mark the future cleavage …

The actin cytoskeleton is a complex network of dynamic polymers, which plays an important
role in various fundamental cellular processes, including maintenance of cell shape …

The contractile ring is a complex molecular apparatus which physically divides many
eukaryotic cells. Despite knowledge of its protein composition, the molecular architecture of …

How the actin cytoskeleton assembles into different structures to drive diverse cellular
processes is a fundamental cell biological question. In addition to orchestrating the …

Through the coordinated action of diverse actin-binding proteins, cells simultaneously
assemble actin filaments with distinct architectures and dynamics to drive different …

BAR domain superfamily proteins have emerged as central regulators of dynamic
membrane remodeling, thereby playing important roles in a wide variety of cellular …

Cytokinesis in many eukaryotes involves the contraction of an actomyosin-based contractile
ring,. However, the detailed mechanism of contractile ring contraction is not fully understood …