Background Sinonasal neoplasms, whether benign and malignant, pose a significant
challenge to clinicians and represent a model area for multidisciplinary collaboration in …

The sinonasal structures and their adjacent organs host several functions including vision,
olfaction, nasal respiration and filtration, secretory immunity, facial expression, articulation …

Purpose Optimal integration of local therapy and systemic immune therapy for patients with
mucosal melanoma (MM) is uncertain. We evaluated treatment patterns and outcomes …

Purpose Local failure and distant metastases occur frequently in sinonasal mucosal
melanoma (SNMM). Response rates to chemotherapy are low and targetable mutations are …

Sinonasal cancer is a clinically and histologically heterogeneous group of rare tumors with
generally poor clinical outcomes. Their low incidence hampers the advancement of clinical …

Methods: A literature search was conducted for peer-reviewed articles reporting and
discussing the epidemiology, staging, and management of MMHN. PubMed, Medline …

Head and neck mucosal melanomas have a diverse mutational landscape with low
mutational burden. A molecular subset (∼ 13%) has ROS1 mutations, which is an …

The purpose of this retrospective study was to investigate response of sinonasal mucosal
melanoma (SMM) patients to treatment with immune checkpoint inhibitors (ICI), using hybrid …

The nasal cavities and paranasal sinuses are the site of origin of a wide spectrum of
histologically and clinically distinct disease entities [1, 2]. The classification of tumors arising …

Clival chordomas are rare but aggressive cranial base tumors that arise from notochordal
remnants [1–3] in the clivus and pose significant treatment challenges due to their difficult …