Induced tolerogenic dendritic cells are a powerful immunotherapy for autoimmune disease
that have shown promise in laboratory models of disease and early clinical trials. In contrast …

The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …

Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

The main function of the immune system in health is to protect the host from infection by
microbes and parasites. Because immune responses to nonself bear the risk of unleashing …

The development of therapeutic approaches for the induction of robust, long-lasting and
antigen-specific immune tolerance remains an important unmet clinical need for the …

Dendritic cells (DCs) are the key professional antigen-presenting cells which bridge innate
and adaptive immune responses, inducing the priming and differentiation of naive to effector …

Antigen-specific immune tolerance has been a long-standing goal for immunotherapy for the
treatment of autoimmune diseases and allergies and for the prevention of allograft rejection …

During homeostasis, interactions between tolerogenic dendritic cells (DCs), self-reactive T
cells, and T regulatory cells (Tregs) contribute to maintaining mammalian immune tolerance …

Quercetin, a bioactive flavonoid with anti-inflammatory, immunosuppressive, and protective
properties, is a potential agent for the treatment of rheumatoid arthritis (RA). Collagen …