The human gut microbiome: from association to modulation

TSB Schmidt, J Raes, P Bork - Cell, 2018 - cell.com
Our understanding of the human gut microbiome continues to evolve at a rapid pace, but
practical application of thisknowledge is still in its infancy. This review discusses the type of …

From microbiome composition to functional engineering, one step at a time

SD Burz, S Causevic, A Dal Co… - Microbiology and …, 2023 - Am Soc Microbiol
Communities of microorganisms (microbiota) are present in all habitats on Earth and are
relevant for agriculture, health, and climate. Deciphering the mechanisms that determine …

Unravelling the collateral damage of antibiotics on gut bacteria

L Maier, CV Goemans, J Wirbel, M Kuhn, C Eberl… - Nature, 2021 - nature.com
Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …

[HTML][HTML] A faecal microbiota signature with high specificity for pancreatic cancer

E Kartal, TSB Schmidt, E Molina-Montes… - Gut, 2022 - gut.bmj.com
Background Recent evidence suggests a role for the microbiome in pancreatic ductal
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …

MGnify: the microbiome analysis resource in 2020

AL Mitchell, A Almeida, M Beracochea… - Nucleic acids …, 2020 - academic.oup.com
Abstract MGnify (http://www. ebi. ac. uk/metagenomics) provides a free to use platform for the
assembly, analysis and archiving of microbiome data derived from sequencing microbial …

Drivers and determinants of strain dynamics following fecal microbiota transplantation

TSB Schmidt, SS Li, OM Maistrenko, W Akanni… - Nature medicine, 2022 - nature.com
Fecal microbiota transplantation (FMT) is a therapeutic intervention for inflammatory
diseases of the gastrointestinal tract, but its clinical mode of action and subsequent …

Metagenome-wide association of gut microbiome features for schizophrenia

F Zhu, Y Ju, W Wang, Q Wang, R Guo, Q Ma… - Nature …, 2020 - nature.com
Evidence is mounting that the gut-brain axis plays an important role in mental diseases
fueling mechanistic investigations to provide a basis for future targeted interventions …

IDTAXA: a novel approach for accurate taxonomic classification of microbiome sequences

A Murali, A Bhargava, ES Wright - Microbiome, 2018 - Springer
Background Microbiome studies often involve sequencing a marker gene to identify the
microorganisms in samples of interest. Sequence classification is a critical component of this …

<? mode longmeta?> SPIRE: a Searchable, Planetary-scale mIcrobiome REsource

TSB Schmidt, A Fullam, P Ferretti, A Orakov… - Nucleic Acids …, 2024 - academic.oup.com
Meta'omic data on microbial diversity and function accrue exponentially in public
repositories, but derived information is often siloed according to data type, study or sampled …

The gut microbiome in social anxiety disorder: evidence of altered composition and function

MI Butler, TFS Bastiaanssen, C Long-Smith… - Translational …, 2023 - nature.com
The microbiome-gut-brain axis plays a role in anxiety, the stress response and social
development, and is of growing interest in neuropsychiatric conditions. The gut microbiota …