Acute myeloid leukemia (AML) is a clinically and biologically heterogeneous malignancy
that is primarily treated with combinations of cytarabine and anthracyclines. Although this …

Background: BCL-2 Associated X (BAX) is an important modulator of apoptosis. The
associations between BAX gene polymorphism and cancer susceptibility and prognosis in …

Despite classical environmental risk factors like tobacco, alcohol or viral infection, not all
individuals develop head and neck cancer. Therefore, identification of the genetic …

Timosaponin A-III (TAIII) is a saponin isolated from anemarrhena asphodeloides and
possesses the inhibitory effect on proliferation of multiple tumor cells. In the present study …

Background There is an ongoing search for molecular markers that are specific, sensitive,
and able to predict the stage of prostate cancer (PCa), which is the second most prevalent …

Abstract BCL2 (B-cell leukemia/lymphoma 2) gene functions as antiapoptotic regulatory
element and known to be associated with tumorigenesis. The SNP-938 (C> A)(rs2279115) …

Simple Summary Acute myeloid leukemia (AML) is a hematological neoplasm with a very
poor survival rate. To date, diagnostic tools to monitor individuals at higher risk of …

In mammals, aminoglycoside antibiotic-induced injury to hair cells (HCs) and associated
spiral ganglion neurons (SGNs) is irreversible and eventually leads to permanent hearing …

Solanine is an alkaloid and is the main extract of the traditional Chinese herb, Solanum
nigrum Linn. It has been reported that Solanine has anti-inflammatory and antitumor …

Bcl-2 is critical for tumorigenesis. However, previous studies on the association of Bcl-2
promoter polymorphisms with predisposition to different cancer types are somewhat …