How are individual cell behaviors coordinated toward invariant large-scale anatomical
outcomes in development and regeneration despite unpredictable perturbations …

At present, bone nonunion and delayed union are still difficult problems in orthopaedics.
Since the discovery of bone morphogenetic protein (BMP), it has been widely used in …

Potassium (K+) homeostasis is tightly regulated for optimal cell and organismal health.
Failure to control potassium balance results in disease, including cardiac arrythmias and …

Cell-to-cell communication is a cornerstone of multicellular existence. The ancient
mechanism of sharing information between cells using the conductance of ions across cell …

Skeletal muscle ion channelopathies (SMICs) are a large heterogeneous group of rare
genetic disorders caused by mutations in genes encoding ion channel subunits in the …

Bone-forming cells or osteoblasts play an important role in bone modeling and remodeling
processes. Osteoblast differentiation or osteoblastogenesis is orchestrated by multiple …

Orbital bone damage (OBD) may result in severe post-traumatic enophthalmos,
craniomaxillofacial deformities, vision loss, and intracranial infections. However, it is still a …

Bisphosphonates (BPs) reduce bone pain and fractures by balancing the
osteoblast/osteoclast ratio. The behavior of ion channels in the presence of BPs is not …

A pedigree of subjects presented with frontonasal dysplasia (FND). Genome sequencing
and analysis identified a p. L165F missense variant in the homeodomain of the transcription …

Simple Summary Skull and jaw shape are critical to how an animal eats. The goal of this
work was to examine how facial variation evolves and the genetic basis of these changes …