Recent applications of 1, 3-thiazole core structure in the identification of new lead compounds and drug discovery

A Ayati, S Emami, A Asadipour, A Shafiee… - European Journal of …, 2015 - Elsevier
Thiazole is one of the most important scaffolds in heterocyclic chemistry and drug design
and discovery. It is widely found in diverse pharmacologically active substances and in …

Biological importance of structurally diversified chromenes

M Costa, TA Dias, A Brito, F Proença - European journal of medicinal …, 2016 - Elsevier
Compounds incorporating the chromene scaffold are largely present in natural products and
display a wide variety of biological activities. Their low toxicity combined to the broad …

New pyrazole derivatives containing 1, 2, 4-triazoles and benzoxazoles as potent antimicrobial and analgesic agents

AM Vijesh, AM Isloor, P Shetty, S Sundershan… - European Journal of …, 2013 - Elsevier
Azole class of compounds are well known for their excellent therapeutic properties. Present
paper describes about the synthesis of three series of new 1, 2, 4-triazole and benzoxazole …

Recent developments in azole compounds as antibacterial and antifungal agents

XM Peng, GX Cai, CH Zhou - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Azole compounds are an important class of nitrogen heterocycles with electron-rich
property. This special structure endows azole-based derivatives easily bind with the …

Hantzsch reaction: synthesis and characterization of some new 1, 4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents

AM Vijesh, AM Isloor, SK Peethambar… - European journal of …, 2011 - Elsevier
In the present study two new series of Hantzsch 1, 4-dihydropyridine derivatives (1, 4-DHPs)
containing substituted pyrazole moiety (4a–f and 5a–f) were synthesized by the reaction of 3 …

Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives

AM Vijesh, AM Isloor, S Telkar, SK Peethambar… - European Journal of …, 2011 - Elsevier
In the present study two series of novel imidazole derivatives containing substituted pyrazole
moiety (3a–d and 5a–j) were synthesized. The first series were synthesized by the reaction …

Synthesis and pharmacological evaluation of some novel 2-(5-hydroxy-5-trifluoromethyl-4, 5-dihydropyrazol-1-yl)-4-(coumarin-3-yl) thiazoles

R Aggarwal, S Kumar, P Kaushik, D Kaushik… - European journal of …, 2013 - Elsevier
A series of novel 2-(5-hydroxy-5-trifluoromethyl-4, 5-dihydropyrazol-1-yl)-4-(coumarin-3-yl)
thiazoles (6) were synthesized by condensing 3-(2-bromoacetyl) coumarins (4) with various …

Study on the influences of two thiazole flavor ingredients on Cu corrosion caused by chloride ion

S Mo, HQ Luo, NB Li - Journal of colloid and interface science, 2017 - Elsevier
Green corrosion inhibitors are of great benefit to the protection of pipes or tanks in seawater
systems. The properties of the corrosion inhibitor such as toxicity and anticorrosion …

[HTML][HTML] Synthesis and in vitro biological evaluation of new pyrazole chalcones and heterocyclic diamides as potential anticancer agents

US Rai, AM Isloor, P Shetty, KSR Pai, HK Fun - Arabian Journal of …, 2015 - Elsevier
Synthesis and characterization of new heterocyclic pyrazole chalcones (4a–e) and diamide
(6a–e) derivatives are described. Pyrazole chalcones were synthesized by the reaction of …

[HTML][HTML] Synthesis, characterization and antibacterial activity of some new pyrazole based Schiff bases

S Malladi, AM Isloor, S Isloor, DS Akhila… - Arabian Journal of …, 2013 - Elsevier
In the present study a series of new Schiff bases were synthesized. All the synthesized
compounds were characterized by IR, 1H NMR, mass spectral and elemental analyses …