Recent advances in pyridine scaffold: Focus on chemistry, synthesis, and antibacterial activities
Multidrug‐resistant (MDR) pathogens have created a fatal problem for human health and
antimicrobial treatment. Among the currently available antibiotics, many are inactive against …
antimicrobial treatment. Among the currently available antibiotics, many are inactive against …
A concise review on some synthetic routes and applications of pyridine scaffold compounds
S Abdel-Raheem, A El-Dean… - Current Chemistry …, 2021 - m.growingscience.com
Different methods for the synthesis of pyridine derivatives as well as the chemical reactivity
profiles and structures of these substances are reviewed. The utility of these compounds as …
profiles and structures of these substances are reviewed. The utility of these compounds as …
Zn (II)-catalyzed multicomponent sustainable synthesis of pyridines in air
Herein, we report a Zn (II)-catalyzed solvent-free sustainable synthesis of tri-and tetra-
substituted pyridines using alcohols as the primary feedstock and NH4OAc as the nitrogen …
substituted pyridines using alcohols as the primary feedstock and NH4OAc as the nitrogen …
Recent developments in the synthesis of azaindoles from pyridine and pyrrole building blocks
DR Motati, R Amaradhi, T Ganesh - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
The azaindole chemical scaffold is represented in many biologically active natural products
and synthetic derivatives. Recently, this chemical scaffold yielded several therapeutic agents …
and synthetic derivatives. Recently, this chemical scaffold yielded several therapeutic agents …
Sources, transformations, syntheses, and bioactivities of monoterpene pyridine alkaloids and cyclopenta [c] pyridine derivatives
X Zhang, F Tao, T Cui, C Luo, Z Zhou, Y Huang, L Tan… - Molecules, 2022 - mdpi.com
Monoterpene pyridine alkaloids (MTPAs) are alkaloids derived from iridoid glycosides (IGs).
The common molecular structure of MTPAs is the pyridine ring, while some of them have a …
The common molecular structure of MTPAs is the pyridine ring, while some of them have a …
Selective synthesis of substituted pyridines and pyrimidines through cascade annulation of isopropene derivatives
J Li, J Li, R He, J Liu, Y Liu, L Chen, Y Huang… - Organic Letters, 2022 - ACS Publications
Diverse substituted pyridines and pyrimidines with high selectivity were obtained using a
concise and efficient protocol developed herein. The reaction proceeds via metal-free …
concise and efficient protocol developed herein. The reaction proceeds via metal-free …
Regioselective access to di-and trisubstituted pyridines via a metal-oxidant-solvent-free domino reaction involving 3-chloropropiophenones
A remarkable metal-oxidant-solvent-and base-free domino route for regioselective access to
a wide range of 2, 4-di-and 2, 3, 4/6-trisubstituted pyridines including carbo-and heterocyclic …
a wide range of 2, 4-di-and 2, 3, 4/6-trisubstituted pyridines including carbo-and heterocyclic …
Primary amine C–N bond cleavage for the synthesis of multi-substituted pyridine and pyrrole derivatives
R Zhang, Y Ding, R Ma, X Xiao, R Chen… - Organic Chemistry …, 2023 - pubs.rsc.org
An efficient synthesis of multi-substituted pyridines and pyrroles from aryl methyl ketones
with 1-amino-2-methylpropan-2-ol and 1, 2-diamino-2-methylpropane, respectively, has …
with 1-amino-2-methylpropan-2-ol and 1, 2-diamino-2-methylpropane, respectively, has …
Synthesis of Nitrogen-Containing Heterocyclic Scaffolds through Sequential Reactions of Aminoalkynes with Carbonyls
Sequential reactions of aminoalkynes represent a powerful tool to easily assembly
biologically important polyfunctionalized nitrogen heterocyclic scaffolds. Metal catalysis …
biologically important polyfunctionalized nitrogen heterocyclic scaffolds. Metal catalysis …
Sustainable four-component annulation for the synthesis of 2, 3, 4, 6-tetraarylpyridines
Y Ding, R Ma, XQ Xiao, L Wang… - The Journal of Organic …, 2021 - ACS Publications
A one-pot, four-component annulation of 2, 3, 4, 6-tetraarylpyridines from aromatic
aldehydes, methyl ketones, diaryl ethanones, and ammonium acetate is described. The …
aldehydes, methyl ketones, diaryl ethanones, and ammonium acetate is described. The …