Deep learning for genomics: From early neural nets to modern large language models

T Yue, Y Wang, L Zhang, C Gu, H Xue, W Wang… - International Journal of …, 2023 - mdpi.com
The data explosion driven by advancements in genomic research, such as high-throughput
sequencing techniques, is constantly challenging conventional methods used in genomics …

[HTML][HTML] Deep learning for protein secondary structure prediction: Pre and post-AlphaFold

DP Ismi, R Pulungan - Computational and structural biotechnology …, 2022 - Elsevier
This paper aims to provide a comprehensive review of the trends and challenges of deep
neural networks for protein secondary structure prediction (PSSP). In recent years, deep …

[PDF][PDF] Intelligent techniques and comparative performance analysis of liver disease prediction

SR Veeranki, M Varshney - International Journal of …, 2022 - kalaharijournals.com
Bioinformatics is the process of analysing gene structures living organisms. The complete
characteristics of living organisms whether it is bad or good is completely controlled by the …

Next-step conditioned deep convolutional neural networks improve protein secondary structure prediction

A Busia, N Jaitly - arXiv preprint arXiv:1702.03865, 2017 - arxiv.org
Recently developed deep learning techniques have significantly improved the accuracy of
various speech and image recognition systems. In this paper we show how to adapt some of …

Proteomic analysis of first trimester maternal serum to identify candidate biomarkers potentially predictive of spontaneous preterm birth

AM D'Silva, JA Hyett, JR Coorssen - Journal of proteomics, 2018 - Elsevier
Spontaneous preterm birth (sPTB) remains a major clinical dilemma; current diagnostics and
interventions have not reduced the rate of this serious healthcare burden. This study …

[HTML][HTML] Diagnostic potential of saliva proteome analysis: a review and guide to clinical practice

CV Esteves, WG Campos, MM Souza… - Brazilian Oral …, 2019 - SciELO Brasil
Proteomic techniques have become popular in medicine and dentistry because of their
widespread use in analyzing bodily fluids such as blood, saliva, urine, and gingival …

[HTML][HTML] Protein hydrolysate from underutilized legumes: unleashing the potential for future functional foods

AT Azman, NSM Isa, ZM Zin… - … nutrition and food …, 2023 - ncbi.nlm.nih.gov
Proteins play a vital role in human development, growth, and overall health. Traditionally,
animal-derived proteins were considered the primary source of dietary protein. However, in …

Structure prediction and functional analyses of a thermostable lipase obtained from Shewanella putrefaciens

FI Khan, B Nizami, R Anwer, KR Gu… - Journal of …, 2017 - Taylor & Francis
Previous experimental studies on thermostable lipase from Shewanella putrefaciens
suggested the maximum activity at higher temperatures, but with little information on its …

Computational analysis of sodium-dependent phosphate transporter SLC20A1/PiT1 gene identifies missense variations C573F, and T58A as high-risk deleterious …

G Siva Sankari, R James, F Payva… - Journal of …, 2024 - Taylor & Francis
Abstract SLC20A1/PiT1 is a sodium-dependent inorganic phosphate transporter, initially
recognized as the retroviral receptor for Gibbon Ape Leukemia Virus in humans. SNPs in …

An Enhanced Genetic Algorithm for Ab Initio Protein Structure Prediction

MA Rashid, F Khatib, MT Hoque… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
In-vitro methods for protein structure determination are time-consuming, cost-intensive, and
failure-prone. Because of these expenses, alternative computer-based predictive methods …