Allergenicity of wheat protein in diet: Mechanisms, modifications and challenges

M Liu, J Huang, S Ma, G Yu, A Liao, L Pan… - Food research …, 2023 - Elsevier
Wheat is widely available in people's daily diets. However, some people are currently
experiencing IgE-mediated allergic reactions to wheat-based foods, which seriously impact …

Creating hypo‐/nonallergenic wheat products using processing methods: Fact or fiction?

H Gao, R Jorgensen, R Raghunath… - … Reviews in Food …, 2021 - Wiley Online Library
Wheat allergy is a potentiallylife‐threatening disease that affects millions of people around
the world. Food processing has been shown to influence the allergenicity of wheat and other …

Chronic application of alcohol-soluble gluten extract over undamaged skin causes clinical sensitization for life-threatening anaphylaxis via activation of systemic Th2 …

R Jorgensen, H Gao, S Chandra, V Sundar, J Loy… - Frontiers in …, 2023 - frontiersin.org
Introduction Gluten allergy is a major public health problem that is growing at an alarming
rate. Specific mechanisms underlying sensitization to gluten remain incompletely …

Is Wheat Glutenin Extract Intrinsically Allergenic? Evaluation Using a Novel Adjuvant-Free Mouse Model of Systemic Anaphylaxis

R Jorgensen, H Gao, TS Arul Arasan… - International Journal of …, 2023 - mdpi.com
Wheat is a prominent allergenic food that can trigger life-threatening anaphylaxis. Presently,
it remains unclear whether wheat glutenin (WG) extract possesses inherent sensitization …

An adjuvant-free mouse model using skin sensitization without tape-stripping followed by oral elicitation of anaphylaxis: a novel pre-clinical tool for testing intrinsic …

H Gao, R Jorgensen, R Raghunath, PKW Ng… - Frontiers in …, 2022 - frontiersin.org
Wheat is a major food allergen per the regulatory bodies of various nations. Hypersensitivity
reactions to wheat have been steadily increasing for reasons that are not completely …

Advances in Gluten Hypersensitivity: Novel Dietary-Based Therapeutics in Research and Development

R Jorgensen, SS Devarahalli, Y Shah, H Gao… - International Journal of …, 2024 - mdpi.com
Gluten hypersensitivity is characterized by the production of IgE antibodies against specific
wheat proteins (allergens) and a myriad of clinical allergic symptoms including life …

[HTML][HTML] Glutenin from the Ancient Wheat Progenitor Is Intrinsically Allergenic as It Can Clinically Sensitize Mice for Systemic Anaphylaxis by Activating Th2 Immune …

R Jorgensen, TSA Arasan, MB Srkalovic… - … Journal of Molecular …, 2024 - ncbi.nlm.nih.gov
Wheat allergy is a major type of food allergy with the potential for life-threatening
anaphylactic reactions. Common wheat, Triticum aestivum (hexaploid, AABBDD genome) …

CD3D: a prognostic biomarker associated with immune infiltration and immunotherapeutic response in head and neck squamous cell carcinoma

Z Wei, Y Shen, C Zhou, Y Cao, H Deng, Z Shen - Bioengineered, 2022 - Taylor & Francis
Recent studies have demonstrated that CD3D activates T-cell-related signal transduction
and is associated with the antitumor immune response in several cancers. This study …

A Mouse-Based Method to Monitor Wheat Allergens in Novel Wheat Lines and Varieties Created by Crossbreeding: Proof-of-Concept Using Durum and A. tauschii …

R Jorgensen, R Raghunath, H Gao, E Olson… - International Journal of …, 2022 - mdpi.com
Wheat allergies are potentially life-threatening because of the high risk of anaphylaxis.
Wheats belong to four genotypes represented in thousands of lines and varieties. Monitoring …