Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …

Statins are a family of drugs that are used for treating hyperlipidaemia with a recognized
capacity to prevent cardiovascular disease events. They inhibit β‐hydroxy β‐methylglutaryl …

Background MK-0616 is an oral macrocyclic peptide inhibitor of proprotein convertase
subtilisin/kexin type 9 (PCSK9) in development for the treatment of hypercholesterolemia …

Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

Background Adhering to weight loss interventions is difficult for many people. The majority of
those who are overweight or obese and attempt to lose weight are simply not successful …

Nonadherence with medication occurs in all chronic medical disorders. It is a particular
challenge in schizophrenia due to the illness's association with social isolation, stigma, and …

Abstract Purpose of Review The aim of creating an orally active non-statin cholesterol-
lowering drug was achieved with bempedoic acid, a small linear molecule providing both a …

Introducción: la falta de adherencia al tratamiento en el contexto de las enfermedades
crónicas es considerada como un grave problema de salud. Objetivo: examinar los …

Background Medication nonadherence is a global problem that requires urgent attention.
Primary nonadherence occurs when a patient consults with a medical doctor, receives a …

Background: The ORION-1 trial (Trial to Evaluate the Effect of ALN-PCSSC Treatment on
Low Density Lipoprotein Cholesterol [LDL-C]) demonstrated that inclisiran, an siRNA …