Toward next generation lateral flow assays: Integration of nanomaterials

A Sena-Torralba, R Álvarez-Diduk, C Parolo… - Chemical …, 2022 - ACS Publications
Lateral flow assays (LFAs) are currently the most used point-of-care sensors for both
diagnostic (eg, pregnancy test, COVID-19 monitoring) and environmental (eg, pesticides …

Aptamer–protein interactions: from regulation to biomolecular detection

C Ji, J Wei, L Zhang, X Hou, J Tan, Q Yuan… - Chemical …, 2023 - ACS Publications
Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Aptamers 101: aptamer discovery and in vitro applications in biosensors and separations

LF Yang, M Ling, N Kacherovsky, SH Pun - Chemical Science, 2023 - pubs.rsc.org
Aptamers are single-stranded nucleic acids that bind and recognize targets much like
antibodies. Recently, aptamers have garnered increased interest due to their unique …

Real-Time, In Vivo Molecular Monitoring Using Electrochemical Aptamer Based Sensors: Opportunities and Challenges

AM Downs, KW Plaxco - ACS sensors, 2022 - ACS Publications
The continuous, real-time measurement of specific molecules in situ in the body would
greatly improve our ability to understand, diagnose, and treat disease. The vast majority of …

Aptamer-based biosensors for virus protein detection

B Lou, Y Liu, M Shi, J Chen, K Li, Y Tan, L Chen… - TrAC Trends in …, 2022 - Elsevier
Virus threatens life health seriously. The accurate early diagnosis of the virus is vital for
clinical control and treatment of virus infection. Aptamers are small single-stranded …

Convection driven ultrarapid protein detection via nanobody‐functionalized organic electrochemical transistors

A Koklu, S Wustoni, K Guo, R Silva… - Advanced …, 2022 - Wiley Online Library
Conventional biosensors rely on the diffusion‐dominated transport of the target analyte to
the sensor surface. Consequently, they require an incubation step that may take several …

Low-cost biosensor technologies for rapid detection of COVID-19 and future pandemics

WR de Araujo, H Lukas, MDT Torres, W Gao… - ACS …, 2024 - ACS Publications
Many systems have been designed for the detection of SARS-CoV-2, which is the virus that
causes COVID-19. SARS-CoV-2 is readily transmitted, resulting in the rapid spread of …

Development of Nucleic‐Acid‐Based Electrochemical Biosensors for Clinical Applications

Z Zhang, P Sen, BR Adhikari, Y Li… - Angewandte …, 2022 - Wiley Online Library
Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …

A folding-based electrochemical aptasensor for the single-step detection of the SARS-CoV-2 spike protein

F Curti, S Fortunati, W Knoll, M Giannetto… - … applied materials & …, 2022 - ACS Publications
Efficient and timely testing has taken center stage in the management, control, and
monitoring of the current COVID-19 pandemic. Simple, rapid, cost-effective diagnostics are …

Development of the DNA-based biosensors for high performance in detection of molecular biomarkers: More rapid, sensitive, and universal

Q Wang, J Wang, Y Huang, Y Du, Y Zhang… - Biosensors and …, 2022 - Elsevier
The molecular biomarkers are molecules that are closely related to specific physiological
states. Numerous molecular biomarkers have been identified as targets for disease …