High-throughput glycomic methods

I Trbojević-Akmačić… - Chemical …, 2022 - ACS Publications
Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

IgG N-glycans

S Liu, X Liu - Advances in clinical chemistry, 2021 - Elsevier
Glycosylation, one of the most common post-translational modifications in mammalian cells,
impacts many biological processes such as cell adhesion, proliferation and differentiation …

Profile of Immunoglobulin G N-Glycome in COVID-19 Patients: A Case-Control Study

H Hou, H Yang, P Liu, C Huang, M Wang, Y Li… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) remains a major health challenge globally. Previous
studies have suggested that changes in the glycosylation of IgG are closely associated with …

Type 2 diabetes mellitus is associated with the immunoglobulin G N-glycome through putative proinflammatory mechanisms in an Australian population

X Li, H Wang, A Russell, W Cao, X Wang… - Omics: a journal of …, 2019 - liebertpub.com
Type 2 diabetes mellitus (T2DM) is a common complex trait arising from interactions among
multiple environmental, genomic, and postgenomic factors. We report here the first attempt …

[HTML][HTML] High-throughput profiling of serological immunoglobulin G N-glycome as a noninvasive biomarker of gastrointestinal cancers

P Liu, X Wang, A Dun, Y Li, H Li, L Wang, Y Zhang, C Li… - Engineering, 2023 - Elsevier
Abstract Immunoglobulin G (IgG) N-glycosylation plays a crucial role in the development of
inflammatory diseases. This study aimed to evaluate the diagnostic performance of IgG for …

Associations of serum iron and ferritin with hyperuricemia and serum uric acid

Y Wang, Z Yang, J Wu, D Xie, T Yang, H Li… - Clinical Rheumatology, 2020 - Springer
Objectives To assess the serum iron and ferritin levels in relation to the prevalence of
hyperuricemia (HU) and the serum uric acid (SUA) level. Methods Serum iron and ferritin …

[HTML][HTML] Predicting Biochemical and Physiological Parameters: Deep Learning from IgG Glycome Composition

A Vujić, M Klasić, G Lauc, O Polašek, V Zoldoš… - International journal of …, 2024 - mdpi.com
In immunoglobulin G (IgG), N-glycosylation plays a pivotal role in structure and function. It is
often altered in different diseases, suggesting that it could be a promising health biomarker …

Association Between Immunoglobulin G N-glycosylation and Vascular Cognitive Impairment in a Sample With Atherosclerosis: A Case-Control Study

M Wang, X Chen, Z Tang, W Zhang, H Hou… - Frontiers in Aging …, 2022 - frontiersin.org
Background Atherosclerosis is considered a crucial component in the pathogenesis of
decreased cognitive function, as occurs in vascular cognitive impairment (VCI). Inflammation …

Glycosylation profiling as a biomarker of suboptimal health status for chronic disease stratification

X Wang, Z Zhong, L Balmer, W Wang - The Role of Glycosylation in Health …, 2021 - Springer
WHO defines health as “a state of complete physical, mental, and social well-being and not
merely the absence of disease or infirmity.” We coined and defined suboptimal health status …

The association between plasma IgG N-glycosylation and neonatal hypoxic–ischemic encephalopathy: a case-control study

L Wang, X Lu, M Wang, X Zhao, P Li… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Hypoxic-ischemic encephalopathy (HIE) is one of severe neonatal brain
injuries, resulting from inflammation and the immune response after perinatal hypoxia and …