Background Tauopathies are a class of neurodegenerative disorders characterized by
neuronal and/or glial tau-positive inclusions. Main body Clinically, tauopathies can present …

Before the controversial approval of humanized monoclonal antibody lecanemab, which
binds to the soluble amyloid‐β protofibrils, all the treatments available earlier, for …

Amyloid fibrils and hyperphosphorylated tau tangles are widely acceptable histological and
biochemical pathogenic markers in Alzheimer's Disease (AD). Detecting these markers at an …

In the last decades, the role of the prion protein (PrP) in neurodegenerative diseases has
been intensively investigated, initially in prion diseases of humans (eg, Creutzfeldt-Jakob …

The central role of oligomers, small soluble aggregates of misfolded proteins, in the
pathogenesis of neurodegenerative disorders is recognized in numerous experimental …

Tauopathies encompass a group of approximately 20 neurodegenerative diseases
characterized by the accumulation of the microtubule-associated protein tau in brain …

Clinical relevance of miRNAs as biomarkers is growing due to their stability and detection in
biofluids. In this, diagnosis at asymptomatic stages of Alzheimer's disease (AD) remains a …

Alzheimer's disease (AD) is a tauopathy characterized by the deposition of amyloid
aggregates of hyperphosphorylated Tau protein and amyloid-β peptide (Aβ) in the brain …

The presence of prion infectivity in the blood of patients affected by variant Creutzfeldt–
Jakob disease (v-CJD), the human prion disease linked to the bovine spongiform …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder whose early
diagnosis leads to a chance for successful treatment and decreases the side effects …